Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 15/20 | 0.60 |
| ▸ | CSNK1D | P48730 | 15/20 | 0.60 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18171287 | 0.91 | CSNK1E (0.72) | CSNK1ECSNK1D | |
| SCHEMBL16728847 | 0.82 | CSNK1E (0.79) | CSNK1ECSNK1D | |
| SCHEMBL16728838 | 0.81 | CSNK1E (0.78) | CSNK1ECSNK1D | |
| SCHEMBL16722631 | 0.79 | CSNK1E (0.77) | CSNK1ECSNK1D | |
| SCHEMBL16728780 | 0.78 | CSNK1E (0.76) | CSNK1ECSNK1D | |
| SCHEMBL18183930 | 0.78 | CSNK1E (0.76) | CSNK1ECSNK1D | |
| SCHEMBL16722713 | 0.78 | CSNK1E (0.75) | CSNK1ECSNK1D | |
| SCHEMBL16728613 | 0.78 | CSNK1E (0.74) | CSNK1ECSNK1D | |
| SCHEMBL16711376 | 0.77 | CSNK1E (0.53) | CSNK1ECSNK1D | |
| SCHEMBL16711296 | 0.77 | CSNK1E (0.53) | CSNK1ECSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015073767-A1 | SUBSTITUTED 4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS CASEIN KINASE 1 D/E INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-05-21 | — | — | WO | disclosed |