Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14959561 | 1.00 | TDP1 (0.35) | TDP1LMNAL3MBTL1TSHR | |
| SCHEMBL10200778 | 1.00 | TDP1 (0.35) | TDP1LMNAL3MBTL1TSHR | |
| SCHEMBL2600227 | 1.00 | TDP1 (0.35) | TDP1LMNAL3MBTL1TSHR | |
| SCHEMBL15267652 | 0.86 | TSHR (0.33) | TDP1LMNATSHR | |
| SCHEMBL14839145 | 0.86 | TDP1 (0.35) | TDP1LMNAL3MBTL1TSHR | |
| SCHEMBL18221666 | 0.86 | TDP1 (0.35) | TDP1LMNAL3MBTL1TSHR | |
| SCHEMBL13512903 | 0.86 | TDP1 (0.35) | TDP1LMNAL3MBTL1TSHR | |
| SCHEMBL16729400 | 0.85 | TDP1 (0.31) | TDP1 | |
| SCHEMBL19277005 | 0.81 | TDP1 (0.35) | TDP1LMNAL3MBTL1TSHR | |
| SCHEMBL18934170 | 0.81 | TDP1 (0.35) | TDP1LMNAL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9469864-B2 | Reversible natural product glycosyltransferase-catalyzed reactions, compounds and related methods | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2016-10-18 | — | — | US | disclosed |
| US-20150141294-A1 | REVERSIBLE NATURAL PRODUCT GLYCOSYLTRANSFERASE-CATALYZED REACTIONS, COMPOUNDS AND RELATED METHODS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-05-21 | — | — | US | disclosed |