Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 20/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 16/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16728579 | 0.82 | CSNK1D (0.35) | CSNK1ECSNK1D | |
| SCHEMBL20748850 | 0.75 | CSNK1E (0.56) | CSNK1ECSNK1D | |
| SCHEMBL16728764 | 0.75 | CSNK1E (0.51) | CSNK1ECSNK1D | |
| SCHEMBL16700137 | 0.74 | CSNK1E (0.61) | CSNK1ECSNK1D | |
| SCHEMBL20748857 | 0.73 | CSNK1E (0.52) | CSNK1ECSNK1D | |
| SCHEMBL16728629 | 0.73 | CSNK1E (0.44) | CSNK1ECSNK1D | |
| SCHEMBL16728825 | 0.72 | CSNK1E (0.56) | CSNK1ECSNK1D | |
| SCHEMBL16730752 | 0.72 | BTK (0.36) | CSNK1ECSNK1D | |
| SCHEMBL16730616 | 0.71 | CSNK1E (0.56) | CSNK1ECSNK1D | |
| SCHEMBL16728639 | 0.71 | CSNK1E (0.48) | CSNK1ECSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015073763-A1 | SUBSTITUTED 4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS CASEIN KINASE 1 D/E INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-05-21 | — | — | WO | disclosed |