Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 17/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 14/20 | 0.42 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16730675 | 0.89 | CSNK1E (0.51) | CSNK1ECSNK1DRIPK2ALDH1A1 | |
| SCHEMBL16711269 | 0.89 | CSNK1E (0.54) | CSNK1ECSNK1DRIPK2 | |
| SCHEMBL16711324 | 0.80 | CSNK1E (0.52) | CSNK1ECSNK1DRIPK2 | |
| SCHEMBL16711520 | 0.79 | CSNK1E (0.65) | CSNK1ECSNK1DRIPK2 | |
| SCHEMBL16711393 | 0.78 | CSNK1E (0.64) | CSNK1ECSNK1D | |
| SCHEMBL16728777 | 0.77 | CSNK1E (0.43) | CSNK1ECSNK1DRIPK2 | |
| SCHEMBL16728617 | 0.77 | CSNK1E (0.42) | CSNK1ECSNK1DRIPK2 | |
| SCHEMBL16711371 | 0.75 | CSNK1E (0.59) | CSNK1ECSNK1D | |
| SCHEMBL16711379 | 0.74 | MAP4K4 (0.36) | — | |
| SCHEMBL30622953 | 0.74 | KCNK3 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015073763-A1 | SUBSTITUTED 4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS CASEIN KINASE 1 D/E INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-05-21 | — | — | WO | disclosed |