Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9965265 | 0.92 | HRH3 (0.62) | HRH3CA12CA1CA2CA9 | |
| SCHEMBL4435583 | 0.90 | ESR1 (0.58) | ESR1FOLH1CA12CA1CA2 | |
| SCHEMBL18828933 | 0.85 | ESR1 (0.61) | ESR1FOLH1CA12CA1CA2 | |
| SCHEMBL14547382 | 0.84 | ESR1 (0.58) | ESR1FOLH1CA12CA1CA2 | |
| SCHEMBL4401285 | 0.81 | HRH3 (0.59) | HRH3CA12CA1CA2CA9 | |
| SCHEMBL9883095 | 0.80 | HRH3 (0.49) | HRH3FOLH1CA12CA1CA2 | |
| SCHEMBL4401282 | 0.79 | FOLH1 (0.60) | ESR1FOLH1CA12CA1CA2 | |
| SCHEMBL4405399 | 0.78 | GBA1 (0.43) | HRH3FOLH1CA12CA1CA2 | |
| SCHEMBL16561810 | 0.77 | FOLH1 (0.62) | ESR1FOLH1CA12CA1CA2 | |
| SCHEMBL18950724 | 0.77 | FOLH1 (0.53) | ESR1FOLH1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150140587-A1 | METHOD OF IMMOBILIZING A PROTEIN OR MOLECULE VIA A MUTANT DEHALOGENASE THAT IS BOUND TO AN IMMOBILIZED DEHALOGENASE SUBSTRATE AND LINKED DIRECTLY OR INDIRECTLY TO THE PROTEIN OR MOLECULE | PROMEGA CORP (US) | 2015-05-21 | — | — | US | disclosed |