Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.42 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6222833 | 0.86 | CHRM3 (0.67) | CHRM3TSHRSLC6A1SLC6A13BLM | |
| Hydrochloric Acid SCHEMBL7923304 | 0.85 | CHRM3 (0.65) | CHRM3TSHRSLC6A1SLC6A13BLM | |
| SCHEMBL4869840 | 0.84 | TSHR (0.56) | TSHRBLMADORA1SLC6A2SLC6A4 | |
| SCHEMBL43932 | 0.79 | — | — | |
| SCHEMBL4448027 | 0.79 | KMT2A (0.42) | TSHRADORA1MEN1KMT2AKDM4E | |
| SCHEMBL340678 | 0.78 | HDAC4 (0.47) | TSHRMEN1KMT2AKDM4EMAPT | |
| SCHEMBL23023352 | 0.78 | CHRM3 (0.47) | CHRM3TSHRSLC6A1SLC6A13BLM | |
| SCHEMBL6049107 | 0.77 | HDAC4 (0.48) | TSHRMEN1KMT2AKDM4EMAPT | |
| SCHEMBL73853 | 0.76 | KDM4E (0.46) | TSHRADORA1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11805519 | 0.75 | HDAC4 (0.47) | TSHRMEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015073774-A1 | AZEPANE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS | NOVIRA THERAPEUTICS, INC. (US) | 2015-05-21 | — | — | WO | disclosed |