SCHEMBL1673114

SCHEMBL1673114

O=CC(O)C(O)C(O)COP(=O)(O)OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MPI P34949 1/20 0.54
BTN3A1 O00481 2/20 0.38
ENPP1 P22413 2/20 0.37
PGD P52209 2/20 0.35
ENPP3 O14638 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL321589 1.00 MPI (0.54) MPIBTN3A1ENPP1PGDENPP3
SCHEMBL6814585 0.97 MPI (0.58) MPIBTN3A1PGD
SCHEMBL51474 0.97 MPI (0.58) MPIBTN3A1PGD
SCHEMBL18486487 0.95 MPI (0.53) MPIBTN3A1ENPP1PGDENPP3
SCHEMBL18486551 0.95 MPI (0.53) MPIBTN3A1ENPP1PGDENPP3
SCHEMBL7497003 0.92 MPI (0.56) MPIBTN3A1PGD
SCHEMBL4082210 0.92 MPI (0.56) MPIBTN3A1PGD
SCHEMBL4075118 0.92 MPI (0.56) MPIBTN3A1PGD
SCHEMBL17671360 0.90 MPI (0.54) MPIBTN3A1ENPP1PGDENPP3
SCHEMBL2894537 0.86 MPI (0.60) MPIPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8030096-B2 Water-soluble rhodamine dyes conjugates APPLIED BIOSYSTEMS LLC (US) 2011-10-04 US disclosed
US-20110081688-A1 Water-Soluble Rhodamine Dyes Conjugates Life Technologies Corporation (US) 2011-04-07 US disclosed
US-7795042-B2 Water-soluble rhodamine dye conjugates APPLIED BIOSYSTEMS, LLC (US) 2010-09-14 US disclosed
US-20090305433-A1 Water-Soluble Rhodamine Dye Conjugates APPLIED BIOSYSTEMS INC. (US) 2009-12-10 US disclosed
US-7504496-B2 Water-soluble rhodamine dye conjugates APPLIED BIOSYSTEMS, LLC 2009-03-17 US disclosed
US-20050153355-A1 Water-soluble rhodamine dye conjugates APPLERA CORPORATION (US) 2005-07-14 US disclosed
US-20050107617-A1 Mobility-modifying cyanine dyes APPLERA CORPORATION (US) 2005-05-19 US disclosed
EP-1244749-B1 MOBILITY-MODIFYING CYANINE DYES APPLERA CORP (US) 2004-09-01 EP disclosed
US-6716994-B1 FLUORESCENCE BASED FOUR COLOR NUCLEIC ACID SEQUENCING APPLERA CORPORATION 2004-04-06 US disclosed
EP-1141137-B1 WATER-SOLUBLE RHODAMINE DYES AND CONJUGATES THEREOF APPLERA CORP (US) 2003-10-08 EP disclosed
US-20030055257-A1 Water-soluble rhodamine dye conjugates APPLERA CORPORATION (US) 2003-03-20 US disclosed
EP-1244749-A2 MOBILITY-MODIFYING CYANINE DYES Applera Corporation (US) 2002-10-02 EP disclosed
US-6372907-B1 LABELLED RHODAMINE DYE-POLYPEPTIDE CONJUGATE, OR SALT THEREOF, COMPRISING RHODAMINE-TYPE PARENT XANTHENE RING SUBSTITUTED AT XANTHENE C-9 CARBON WITH SUBSTITUTED PHENYL RING APPTERA CORPORATION 2002-04-16 US disclosed
US-6348596-B1 NUCLEIC ACID HYBRIDIZATION ASSAYS; DNA SEQUENCE DETERMINATION PE CORPORATION (NY) 2002-02-19 US disclosed
WO-2001049790-A2 MOBILITY-MODIFYING CYANINE DYES APPLERA CORPORATION (US) 2001-07-12 WO disclosed
US-6191278-B1 COMPRISING A RHODAMINE-TYPE PARENT RING HAVING ATTACHED TO THE XANTHENE C9 CARBON A PHENYL GROUP THAT IS SUBSTITUTED WITH CARBOXY OR SULFONATE GROUP, ONE TO THREE AMINOPYRIDINIUM GROUPS AND AN ALKYL- OR ARYLTHIO, AND OPTIONALLY OTHER GROUPS PE CORPORATION 2001-02-20 US disclosed
US-6107061-A Modified primer extension reactions for polynucleotide sequence detection THE PERKIN-ELMER CORPORATION (US) 2000-08-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050107617-A1 Mobility-modifying cyanine dyes DNMT3A, POLL, DNASE1 MPI 178/4885BTN3A1 2697/4885ENPP1 2052/4885
US-20050153355-A1 Water-soluble rhodamine dye conjugates SLC43A3, ABCG2, TARBP1 MPI 557/4885BTN3A1 3938/4885ENPP1 2473/4885
US-20030055257-A1 Water-soluble rhodamine dye conjugates SLC43A3, ABCG2, TARBP1 MPI 557/4885BTN3A1 3938/4885ENPP1 2473/4885
US-20090305433-A1 Water-Soluble Rhodamine Dye Conjugates SLC43A3, ABCG2, TARBP1 MPI 557/4885BTN3A1 3938/4885ENPP1 2473/4885
US-20110081688-A1 Water-Soluble Rhodamine Dyes Conjugates SLC43A3, ABCG2, TARBP1 MPI 532/4885BTN3A1 3868/4885ENPP1 2562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.