Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 7/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2212215 | 1.00 | AOC3 (1.00) | AOC3L3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL2212219 | 1.00 | AOC3 (1.00) | AOC3L3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL2210492 | 0.82 | AOC3 (0.78) | AOC3L3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL2210488 | 0.82 | AOC3 (0.78) | AOC3L3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL16735540 | 0.82 | AOC3 (0.78) | AOC3L3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL2208796 | 0.80 | AOC3 (1.00) | AOC3L3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL16735536 | 0.80 | AOC3 (1.00) | AOC3L3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL2207915 | 0.78 | AOC3 (0.64) | AOC3L3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL2209686 | 0.77 | AOC3 (0.62) | AOC3ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL2209693 | 0.77 | AOC3 (0.62) | AOC3ALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342179-B1 | COMPOUNDS FOR INHIBITING SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) / VASCULAR ADHESION PROTEIN-1 (VAP-1) AND USES THEREOF FOR TREATMENT AND PREVENTION OF DISEASES | SEMMELWEIS EGYETEM (HU) | 2015-05-27 | — | — | EP | claimed |