Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1062444 | 0.89 | TLR7 (0.67) | TLR7 | |
| SCHEMBL1062044 | 0.86 | TLR7 (0.62) | TLR7 | |
| SCHEMBL1007686 | 0.85 | TLR7 (0.52) | TLR7 | |
| SCHEMBL1056246 | 0.84 | TLR7 (0.55) | TLR7 | |
| SCHEMBL16735801 | 0.84 | TLR7 (0.53) | TLR7 | |
| SCHEMBL1009182 | 0.84 | TLR7 (0.77) | TLR7 | |
| SCHEMBL13449543 | 0.83 | TLR7 (0.58) | TLR7 | |
| SCHEMBL1010175 | 0.82 | TLR7 (0.68) | TLR7 | |
| SCHEMBL1675542 | 0.82 | TLR7 (0.57) | TLR7 | |
| SCHEMBL1008112 | 0.82 | TLR7 (0.58) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268618-B1 | COMPOUNDS AND COMPOSITIONS AS TLR ACTIVITY MODULATORS | NOVARTIS AG (CH) | 2015-05-27 | — | — | EP | disclosed |