Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29401979 | 0.80 | TSHR (0.42) | TSHRTHRBDNM1TRPM8OPRM1 | |
| SCHEMBL11368821 | 0.76 | TSHR (0.38) | TSHRTHRBDNM1TRPM8OPRM1 | |
| SCHEMBL14162212 | 0.70 | TSHR (0.42) | TSHRTHRBDNM1TRPM8OPRM1 | |
| SCHEMBL14162085 | 0.70 | TSHR (0.42) | TSHRTHRBDNM1TRPM8OPRM1 | |
| SCHEMBL19820434 | 0.69 | TSHR (0.47) | TSHRTHRBDNM1EPHX1ALDH1A1 | |
| SCHEMBL16602995 | 0.69 | TSHR (0.33) | TSHRTHRBOPRM1LMNA | |
| SCHEMBL25241608 | 0.68 | TSHR (0.53) | TSHRTHRBDNM1EPHX1ALDH1A1 | |
| SCHEMBL11136138 | 0.68 | TSHR (0.53) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL11134007 | 0.68 | TSHR (0.53) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL5664939 | 0.68 | TSHR (0.53) | TSHRTHRBDNM1EPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071586-A1 | COBALT CATALYSTS AND THEIR USE FOR HYDROSILYLATION AND DEHYDROGENATIVE SILYLATION | Momentive Performance Materials Inc. (US) | 2016-09-28 | — | — | EP | disclosed |
| WO-2015077306-A1 | COBALT CATALYSTS AND THEIR USE FOR HYDROSILYLATION AND DEHYDROGENATIVE SILYLATION | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2015-05-28 | — | — | WO | disclosed |