SCHEMBL16742986

SCHEMBL16742986

C=C(C)C(=O)N(CCS)C(=O)C(=C)C

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2184776 0.78 MAPT (0.33) TDP1
SCHEMBL4380617 0.78 TDP1 (0.33) TDP1
SCHEMBL318875 0.77 PAOX (0.36)
SCHEMBL672541 0.76 TDP1 (0.38) TDP1
SCHEMBL6928524 0.74 CHRM1 (0.42) TDP1
SCHEMBL9424899 0.73 CA12 (0.32)
SCHEMBL11417281 0.72 TDP1 (0.36) TDP1
SCHEMBL8909687 0.71
SCHEMBL8973647 0.68 CA12 (0.35) TDP1
SCHEMBL10783976 0.68 TDP1 (0.36) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3071185-A1 MULTI-RESPONSIVE TARGETING DRUG DELIVERY SYSTEMS FOR CONTROLLED-RELEASE PHARMACEUTICAL FORMULATION Kordas, George (GR) 2016-09-28 EP disclosed
US-20160263221-A1 MULTI-RESPONSIVE TARGETING DRUG DELIVERY SYSTEMS FOR CONTROLLED-RELEASE PHARMACEUTICAL FORMULATION KORDAS GEORGE (GR) 2016-09-15 US disclosed
WO-2015074762-A9 MULTI-RESPONSIVE TARGETING DRUG DELIVERY SYSTEMS FOR CONTROLLED-RELEASE PHARMACEUTICAL FORMULATION KORDAS GEORGE (GR) 2015-09-24 WO disclosed
WO-2015074762-A1 MULTI-RESPONSIVE TARGETING DRUG DELIVERY SYSTEMS FOR CONTROLLED-RELEASE PHARMACEUTICAL FORMULATION KORDAS GEORGE (GR) 2015-05-28 WO disclosed