Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 19/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16743065 | 0.98 | CETP (0.43) | CETPTBXA2RPTGDRPTGDR2 | |
| SCHEMBL16743069 | 0.97 | CETP (0.44) | CETPTBXA2RPTGDRPTGDR2 | |
| SCHEMBL5623604 | 0.95 | CETP (0.47) | CETPTBXA2RPTGDRPTGDR2 | |
| SCHEMBL19440358 | 0.94 | CETP (0.38) | CETPTBXA2RPTGDRPTGDR2 | |
| SCHEMBL5624969 | 0.94 | CETP (0.47) | CETPTBXA2RPTGDRPTGDR2 | |
| SCHEMBL5623759 | 0.92 | CETP (0.48) | CETPTBXA2RPTGDRPTGDR2 | |
| SCHEMBL16743066 | 0.92 | CETP (0.38) | CETP | |
| SCHEMBL16743073 | 0.91 | CETP (0.47) | CETPTBXA2RPTGDRPTGDR2 | |
| SCHEMBL16743064 | 0.91 | CETP (0.49) | CETPTBXA2RPTGDRPTGDR2 | |
| SCHEMBL5625992 | 0.90 | CETP (0.40) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9782407-B2 | Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors | DR. REDDY'S LABORATORIES LTD. (IN) | 2017-10-10 | — | — | US | disclosed |
| US-20170071930-A1 | PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS | DR. REDDY'S LABORATORIES, LTD. (IN) | 2017-03-16 | — | — | US | disclosed |
| US-20160000799-A1 | PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS | DR. REDDY'S LABORATORIES, LTD. (IN) | 2016-01-07 | — | — | US | disclosed |
| US-20150216866-A1 | SUBSTITUTED BENZYLAMINO QUINOLINES AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2015-08-06 | — | — | US | disclosed |
| US-9040558-B2 | Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors | DR. REDDY'S LABORATORIES LTD. (IN) | 2015-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150216866-A1 | SUBSTITUTED BENZYLAMINO QUINOLINES AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | CETP, NPC1, MTTP | CETP 1/4885TBXA2R 1958/4885PTGDR 4721/4885 |
| US-20160000799-A1 | PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS | CETP, LCAT, MTTP | CETP 1/4885TBXA2R 2918/4885PTGDR 4725/4885 |
| US-20170071930-A1 | PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS | CETP, NPC1, CES1 | CETP 1/4885TBXA2R 1549/4885PTGDR 3990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.