Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15910600 | 0.89 | SYK (1.00) | SYK | |
| SCHEMBL14839074 | 0.87 | SYK (1.00) | SYK | |
| SCHEMBL14839005 | 0.85 | SYK (0.81) | SYK | |
| SCHEMBL15910909 | 0.83 | SYK (0.89) | SYK | |
| SCHEMBL14839013 | 0.83 | SYK (0.70) | SYK | |
| SCHEMBL14838956 | 0.81 | SYK (0.79) | SYK | |
| SCHEMBL16743231 | 0.81 | SYK (0.71) | SYK | |
| SCHEMBL14838960 | 0.80 | SYK (0.88) | SYK | |
| SCHEMBL15910966 | 0.80 | SYK (1.00) | SYK | |
| SCHEMBL14912305 | 0.80 | SYK (0.59) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040530-B2 | 1,2,4-triazine-6-carboxamide kinase inhibitors | PORTOLA PHARMACEUTICALS, INC. (US) | 2015-05-26 | — | — | US | disclosed |
| US-9040530-B2 | 1,2,4-triazine-6-carboxamide kinase inhibitors | PORTOLA PHARMACEUTICALS, INC. (US) | 2015-05-26 | — | — | US | disclosed |