SCHEMBL1674394

SCHEMBL1674394

Cc1[nH]c(=O)[nH]c(=O)c1[N+](=O)[O-]

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 11/20 0.44
KMT2A Q03164 11/20 0.44
POLB P06746 4/20 0.44
GALK1 P51570 2/20 0.42
GRIN2D O15399 5/20 0.40
GRIN3B O60391 5/20 0.40
GRIN1 Q05586 5/20 0.40
GRIN2A Q12879 5/20 0.40
GRIN2B Q13224 5/20 0.40
GRIN2C Q14957 5/20 0.40
GRIN3A Q8TCU5 5/20 0.40
MAPT P10636 2/20 0.39
GAA P10253 1/20 0.39
KDM4E B2RXH2 1/20 0.39
USP2 O75604 1/20 0.39
PKM P14618 1/20 0.39
APEX1 P27695 1/20 0.39
RECQL P46063 1/20 0.39
BLM P54132 1/20 0.39
CASP7 P55210 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9710117 0.82 MEN1 (0.34) MEN1KMT2APOLBGALK1GRIN2D
SCHEMBL11737754 0.79 KDM4E (0.41) POLBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL5826221 0.74 TYMP (0.45) MEN1KMT2APOLBGALK1GRIN2D
SCHEMBL14608804 0.74 MEN1 (0.47) MEN1KMT2APOLBGALK1GRIN2D
SCHEMBL15218850 0.74 MEN1 (0.43) MEN1KMT2APOLBGALK1GRIN2D
SCHEMBL27853984 0.74 MEN1 (0.41) MEN1KMT2APOLBGALK1GRIN2D
SCHEMBL11676489 0.74 KMT2A (0.49) MEN1KMT2APOLBGALK1GRIN2D
SCHEMBL15222158 0.74 MEN1 (0.41) MEN1KMT2APOLBGALK1GRIN2D
SCHEMBL17260125 0.73 MAPT (0.43) POLBGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL15222187 0.70 KMT2A (0.43) MEN1KMT2APOLBGALK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4560315-A2 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES F. Hoffmann-La Roche AG (CH) 2025-05-28 EP claimed
EP-3980554-B1 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES HOFFMANN LA ROCHE (CH) 2025-03-26 EP claimed
CN-115050893-A Perovskite solar cell based on alkaloid additive 安徽大学 2022-09-13 CN claimed
US-20220195497-A1 HYBRIDIZING all-LNA OLIGONUCLEOTIDES ROCHE DIAGNOSTICS OPERATIONS, INC. 2022-06-23 US claimed
EP-3980554-A1 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES F. Hoffmann-La Roche AG (CH) 2022-04-13 EP claimed
CN-113939599-A Hybrid all-LNA oligonucleotides 豪夫迈·罗氏有限公司 2022-01-14 CN claimed
EP-4560315-A2 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES F. Hoffmann-La Roche AG (CH) 2025-05-28 EP disclosed
EP-3980554-B1 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES HOFFMANN LA ROCHE (CH) 2025-03-26 EP disclosed
CN-115050893-A Perovskite solar cell based on alkaloid additive 安徽大学 2022-09-13 CN disclosed
US-20220195497-A1 HYBRIDIZING all-LNA OLIGONUCLEOTIDES ROCHE DIAGNOSTICS OPERATIONS, INC. 2022-06-23 US disclosed
EP-3980554-A1 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES F. Hoffmann-La Roche AG (CH) 2022-04-13 EP disclosed
EP-3526199-B1 INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE TES PHARMA S R L (IT) 2022-04-13 EP disclosed
CN-113939599-A Hybrid all-LNA oligonucleotides 豪夫迈·罗氏有限公司 2022-01-14 CN disclosed
EP-0736569-A1 Derivatives of pyrrolodiazine as stabilisers for polymers containing chlorine CIBA-GEIGY AG (CH) 1996-10-09 EP disclosed
US-5389641-A Fused heterocyclic compounds, having angiotensin II antagonistic activity TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-02-14 US disclosed
US-5213972-A Production of thymidine and deoxyuridine, intermediates for AZT CHEMGEN CORPORATION (US) 1993-05-25 US disclosed
EP-0504279-A4 FERMENTATION PROCESS FOR THE PRODUCTION OF PYRIMIDINE DEOXYRIBONUCLEOSIDES 1993-02-17 EP disclosed
EP-0518033-A1 Fused heterocyclic compounds, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-12-16 EP disclosed
EP-0504279-A1 FERMENTATION PROCESS FOR THE PRODUCTION OF PYRIMIDINE DEOXYRIBONUCLEOSIDES. CHEMGEN CORP (US) 1992-09-23 EP disclosed
WO-1991009130-A1 FERMENTATION PROCESS FOR THE PRODUCTION OF PYRIMIDINE DEOXYRIBONUCLEOSIDES CHEMGEN CORPORATION (US) 1991-06-27 WO disclosed