Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.64 |
| ▸ | PPARG | P37231 | 7/20 | 0.64 |
| ▸ | PPARD | Q03181 | 4/20 | 0.61 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | LTA4H | P09960 | 2/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | LAP3 | P28838 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5606931 | 0.90 | PPARA (0.74) | PPARAPPARGPPARDMAOBLTA4H | |
| Ammonia Solution, Strong SCHEMBL5606255 | 0.89 | PPARA (0.72) | PPARAPPARGPPARDMAOBLTA4H | |
| SCHEMBL5607112 | 0.89 | PPARA (0.72) | PPARAPPARGPPARDMAOBLTA4H | |
| SCHEMBL5606778 | 0.89 | PPARA (0.72) | PPARAPPARGPPARDMAOBLTA4H | |
| SCHEMBL5607555 | 0.89 | PPARA (0.72) | PPARAPPARGPPARDMAOBLTA4H | |
| SCHEMBL5606264 | 0.89 | PPARA (0.72) | PPARAPPARGPPARDMAOBLTA4H | |
| SCHEMBL5606732 | 0.89 | PPARA (0.72) | PPARAPPARGPPARDMAOBLTA4H | |
| Rubidium SCHEMBL5607457 | 0.89 | PPARA (0.72) | PPARAPPARGPPARDMAOBLTA4H | |
| SCHEMBL5607451 | 0.89 | PPARA (0.72) | PPARAPPARGPPARDMAOBLTA4H | |
| SCHEMBL5607778 | 0.89 | PPARA (0.72) | PPARAPPARGPPARDMAOBLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040531-B2 | Alpha helix mimetics and methods relating thereto | Prism BioLab Co., Ltd. (JP) | 2015-05-26 | — | — | US | disclosed |