SCHEMBL1674568

SCHEMBL1674568

C=C=NC(N)CC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22444545 0.72
SCHEMBL4791941 0.72
SCHEMBL9157037 0.70
Hydrochloric Acid SCHEMBL5823995 0.70
Hydrochloric Acid SCHEMBL28596074 0.69
SCHEMBL1443231 0.69
SCHEMBL521487 0.67
Hydrochloric Acid SCHEMBL8103830 0.67 CYP1A2 (0.30)
SCHEMBL5911113 0.65
SCHEMBL28130091 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2332998-B1 Solvent free aqueous polyurethane dispersions and methods of making and using the same VERSUM MAT US LLC (US) 2018-09-26 EP disclosed
US-9617453-B2 Solvent free aqueous polyurethane dispersions and methods of making and using the same AIR PRODUCTS AND CHEMICALS, INC. (US) 2017-04-11 US disclosed
CN-102161743-B Solvent-free aqueous polyurethane dispersion and preparation and application thereof AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-04-06 CN disclosed
EP-2308908-B1 Aqueous dispersion of a heat hardened polyurethane composition JANSEN BERNHARD (DE) 2014-06-25 EP disclosed
US-20110306724-A1 Solvent Free Aqueous Polyurethane Dispersions and Methods of Making and Using the Same AIR PRODUCTS AND CHEMICALS, INC. (US) 2011-12-15 US disclosed
CN-102161743-A Solvent free aqueous polyurethane dispersions and methods of making and using the same AIR PROD & CHEM 2011-08-24 CN disclosed
EP-2332998-A1 Solvent free aqueous polyurethane dispersions and methods of making and using the same Air Products and Chemicals, Inc. (US) 2011-06-15 EP disclosed
EP-2308908-A1 Aqueous dispersion of a heat hardened polyurethane composition Jansen, Bernhard (DE) 2011-04-13 EP disclosed
US-20020055602-A1 Aromatic polyisocyanates blocked by pyrazole or pyrazole derivatives and the preparation and use thereof BAYER AKTIENGESELLSCHAFT (DE) 2002-05-09 US disclosed
EP-1184400-A1 Aromatic polyisocyanates blocked with pyrazole or pyrazole derivatives, process for their preparation and their use BAYER AG (DE) 2002-03-06 EP disclosed
US-4544683-A GYPSUM-POLYURETHANE OR POLYURETHANE-POLYUREA BAYER AKTIENGESELLSCHAFT (DE) 1985-10-01 US disclosed
EP-0128399-A2 Support dressing and process for its manufacture BAYER AG (DE) 1984-12-19 EP disclosed
US-4324716-A -POLYURETHANE FOAMS BAYER AKTIENGESELLSCHAFT (DE) 1982-04-13 US disclosed
US-4310448-A POLYETHER OR POLYESTER DISPERSANTS FOR POLYURETHANES OR POLUREAS BAYER AKTIENGESELLSCHAFT (DE) 1982-01-12 US disclosed
US-4310449-A Process for the preparation of stable dispersions BAYER AKTIENGESELLSCHAFT (DE) 1982-01-12 US disclosed
US-4305858-A Process for the preparation of stable ionic dispersions of polyisocyanate-polyaddition products in hydroxyl containing compounds BAYER AKTIENGESELLSCHAFT (DE) 1981-12-15 US disclosed
US-4184990-A Process for the preparation of stable dispersions of polyisocyanate-polyaddition products in a hydroxyl containing compound as dispersing agent BAYER AKTIENGESELLSCHAFT (DE) 1980-01-22 US disclosed
US-4147680-A Production of polyurethane resins using as active hydrogen material a stable dispersion of ionic polyisocyanate-polyaddition products in hydroxyl containing compounds as a dispersing agent BAYER AKTIENGESELLSCHAFT (DE) 1979-04-03 US disclosed
US-4092275-A Polyurethane resins prepared from active hydrogen containing material which is a dispersion of polyisocyanate-polyaddition products in hydroxyl containing compounds as dispersing agents BAYER AKTIENGESELLSCHAFT (DT) 1978-05-30 US disclosed
US-3970601-A COATINGS BAYER AKTIENGESELLSCHAFT (DT) 1976-07-20 US disclosed