Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.59 |
| ▸ | CA2 | P00918 | 7/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16747298 | 0.99 | CA1 (0.57) | CA1CA2CA12CA9HPGD | |
| SCHEMBL15036575 | 0.96 | CA1 (0.57) | CA1CA2CA12CA9ACHE | |
| SCHEMBL16747185 | 0.86 | MEN1 (0.56) | CA1CA2CA12CA9TGM2 | |
| SCHEMBL29243230 | 0.86 | CA1 (0.53) | CA1CA2CA12CA9ACHE | |
| SCHEMBL29460302 | 0.85 | CA1 (0.52) | CA1CA2CA12CA9ACHE | |
| SCHEMBL10350776 | 0.82 | CA1 (0.55) | CA1CA2CA12CA9TSHR | |
| SCHEMBL13400313 | 0.81 | CA12 (0.48) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL14690519 | 0.81 | CA1 (0.53) | CA1CA2CA12CA9ACHE | |
| SCHEMBL15036576 | 0.81 | CA1 (0.53) | CA1CA2CA12CA9ACHE | |
| SCHEMBL10351044 | 0.81 | CA1 (0.50) | CA1CA2CA12CA9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2876105-A1 | 1-(CYCLOALKYL-CARBONYL)PROLINE DERIVATIVE | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2015-05-27 | — | — | EP | disclosed |