SCHEMBL16748124

SCHEMBL16748124

Cc1ccc(C(=O)OOC(=O)c2cccc(C)c2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.53
F2 P00734 1/20 0.52
LMNA P02545 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
RAB9A P51151 6/20 0.50
NPC1 O15118 5/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
PKM P14618 1/20 0.50
HTT P42858 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
KMT2A Q03164 3/20 0.49
POLB P06746 2/20 0.49
MEN1 O00255 2/20 0.49
ESR1 P03372 2/20 0.49
ESR2 Q92731 1/20 0.49
ADRB2 P07550 2/20 0.48
ADRB1 P08588 2/20 0.48
ADRB3 P13945 2/20 0.48
CES2 O00748 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7943563 1.00 PARP1 (0.53) PARP1F2LMNATDP1RAB9A
SCHEMBL29397067 0.92 PARP1 (0.61) PARP1F2LMNATDP1RAB9A
SCHEMBL44313 0.92 PARP1 (0.61) PARP1F2LMNATDP1RAB9A
Benzoyl Peroxide SCHEMBL10925823 0.91 F2 (0.65) PARP1F2LMNATDP1NPC1
SCHEMBL329271 0.91 F2 (0.65) PARP1F2LMNATDP1NPC1
SCHEMBL29390229 0.91 F2 (0.65) PARP1F2LMNATDP1NPC1
SCHEMBL11488211 0.89 PARP1 (0.53) PARP1TDP1RAB9ANPC1SMN1; SMN2
SCHEMBL4106027 0.87 CNR2 (0.53) PARP1F2LMNATDP1RAB9A
Benzoic Acid SCHEMBL29214446 0.86 F2 (0.59) PARP1F2LMNATDP1NPC1
SCHEMBL7625518 0.85 PARP1 (0.53) PARP1F2LMNATDP1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10196539-B2 Thermosetting powder coating compositions comprising methyl-substituted benzoyl peroxide DSM IP ASSETS B.V. (NL) 2019-02-05 US disclosed
EP-3071651-B1 THERMOSETTING POWDER COATING COMPOSITIONS COMPRISING METHYL-SUBSTITUTED BENZOYL PEROXIDE DSM IP ASSETS BV (NL) 2017-12-20 EP disclosed
US-20160264817-A1 THERMOSETTING POWDER COATING COMPOSITIONS COMPRISING METHYL-SUBSTITUTED BENZOYL PEROXIDE DSM IP ASSETS B.V. (NL) 2016-09-15 US disclosed
US-20160264817-A1 THERMOSETTING POWDER COATING COMPOSITIONS COMPRISING METHYL-SUBSTITUTED BENZOYL PEROXIDE DSM IP ASSETS B.V. (NL) 2016-09-15 US disclosed
WO-2015075186-A1 THERMOSETTING POWDER COATING COMPOSITIONS COMPRISING METHYL-SUBSTITUTED BENZOYL PEROXIDE DSM IP ASSETS B.V. (NL) 2015-05-28 WO disclosed