Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 13/20 | 0.65 |
| ▸ | IGF1R | P08069 | 6/20 | 0.52 |
| ▸ | BTK | Q06187 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16748832 | 0.93 | TNK2 (0.65) | TNK2IGF1RBTKCYP3A4MAPK3 | |
| SCHEMBL18099760 | 0.84 | TNK2 (0.66) | TNK2IGF1RBTKCYP3A4MAPK3 | |
| SCHEMBL16748813 | 0.82 | BTK (0.67) | TNK2BTK | |
| SCHEMBL16748848 | 0.81 | BTK (0.65) | TNK2IGF1RBTK | |
| SCHEMBL16748938 | 0.80 | TNK2 (0.63) | TNK2BTK | |
| SCHEMBL1129353 | 0.80 | TNK2 (1.00) | TNK2IGF1RCYP3A4MAPK3MAPK1 | |
| SCHEMBL4360606 | 0.80 | TNK2 (1.00) | TNK2IGF1RCYP3A4MAPK3MAPK1 | |
| SCHEMBL16748810 | 0.80 | BTK (0.63) | TNK2BTK | |
| SCHEMBL16748774 | 0.80 | BTK (0.63) | TNK2BTK | |
| SCHEMBL18099741 | 0.78 | BTK (0.60) | TNK2BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015074138-A1 | PROTEIN KINASE INHIBITORS | PHARMASCIENCE INC. (CA) | 2015-05-28 | — | — | WO | disclosed |