SCHEMBL16748940

SCHEMBL16748940

CCNCCNCCS(=O)(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 0.46
CYP1A2 P05177 1/20 0.46
MEN1 O00255 1/20 0.42
GLA P06280 1/20 0.42
KMT2A Q03164 1/20 0.42
KDM1A O60341 3/20 0.38
LMNA P02545 2/20 0.35
PTGS1 P23219 1/20 0.35
PDE4A P27815 1/20 0.35
TSHR P16473 1/20 0.35
SLC6A6 P31641 1/20 0.35
BLM P54132 1/20 0.35
SAT1 P21673 3/20 0.34
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
LOX P28300 1/20 0.33
EPHX2 P34913 1/20 0.33
CYP2D6 P10635 1/20 0.32
APP P05067 1/20 0.32
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1979880 0.95
SCHEMBL5889198 0.93 CYP2C19 (0.42) CYP2C19CYP1A2MEN1GLAKMT2A
SCHEMBL30026428 0.87 PTGS1 (0.43) CYP2C19LMNAPTGS1PDE4ASLC6A6
SCHEMBL13754311 0.86 PAOX (0.43) CYP2C19LMNAPTGS1PDE4ATSHR
SCHEMBL1805336 0.84 PTGS1 (0.45) CYP2C19LMNAPTGS1PDE4ASLC6A6
SCHEMBL1980068 0.83 PAOX (0.45) CYP2C19LMNAPTGS1PDE4ATSHR
SCHEMBL353650 0.81 CYP2C19 (0.52) CYP2C19CYP1A2MEN1GLAKMT2A
SCHEMBL918515 0.81 CYP2C19 (0.52) CYP2C19CYP1A2MEN1GLAKMT2A
SCHEMBL31217867 0.80 TSHR (0.48) TSHRCA1CA2EPHX2
Trolamine SCHEMBL28288911 0.80 CYP1A2 (0.32) CYP2C19CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015075300-A1 METHOD OF ANALYSIS AQSENS OY (FI) 2015-05-28 WO disclosed