⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9576819 | 0.74 | — | — | |
| SCHEMBL7794282 | 0.70 | — | — | |
| SCHEMBL7803139 | 0.70 | — | — | |
| SCHEMBL5405506 | 0.70 | — | — | |
| SCHEMBL1402338 | 0.70 | — | — | |
| SCHEMBL588632 | 0.70 | — | — | |
| SCHEMBL87714 | 0.67 | — | — | |
| SCHEMBL130701 | 0.67 | — | — | |
| SCHEMBL567822 | 0.67 | — | — | |
| Glycerin SCHEMBL10481848 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116333284-A | Preparation method of high-refractive-index copolyester | 万凯新材料股份有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-112574399-B | High-temperature-resistant polycyclic aromatic hydrocarbon polyester hollow container and preparation method thereof | 中国科学院宁波材料技术与工程研究所 | 2021-05-07 | — | — | CN | claimed |
| CN-112592471-B | High-heat-resistance high-toughness polyester, polyester product, preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2021-05-07 | — | — | CN | claimed |
| CN-112592467-B | High glass transition temperature low melting point polyester, polyester product, and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2021-04-30 | — | — | CN | claimed |
| CN-112592467-A | High glass transition temperature low melting point polyester, polyester product, and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2021-04-02 | — | — | CN | claimed |
| CN-112592471-A | High-heat-resistance high-toughness polyester, polyester product, preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2021-04-02 | — | — | CN | claimed |
| CN-112574399-A | High-temperature-resistant polycyclic aromatic hydrocarbon polyester hollow container and preparation method thereof | 中国科学院宁波材料技术与工程研究所 | 2021-03-30 | — | — | CN | claimed |
| US-20230348438-A1 | PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2023-11-02 | — | — | US | disclosed |
| CN-116333284-A | Preparation method of high-refractive-index copolyester | 万凯新材料股份有限公司 | 2023-06-27 | — | — | CN | disclosed |
| EP-4159212-A1 | P38 KINASE INHIBITORS REDUCE DUX4 AND DOWNSTREAM GENE EXPRESSION FOR THE TREATMENT OF FSHD | Fulcrum Therapeutics, Inc. (US) | 2023-04-05 | — | — | EP | disclosed |
| CN-114748622-A | P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD | 弗尔康医疗公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114732910-A | P38 kinase inhibitor reduces DUX4 and downstream gene expression for treatment of FSHD | 弗尔康医疗公司 | 2022-07-12 | — | — | CN | disclosed |
| US-20220133704-A1 | P38 KINASE INHIBITORS REDUCE DUX4 AND DOWNSTREAM GENE EXPRESSION FOR THE TREATMENT OF FSHD | FULCRUM THERAPEUTICS INC (US) | 2022-05-05 | — | — | US | disclosed |
| US-4931591-A | Novel 5-amino-4-hydroxyvaleryl derivatives | CIBA-GEIGY CORPORATION (US) | 1990-06-05 | — | — | US | disclosed |
| US-4863903-A | RENIN ENZYME INHIBITORS, HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |
| US-4727060-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |
| US-4719288-A | HYPOTENSIVE | CIBA-GEIGY CORPORATION (US) | 1988-01-12 | — | — | US | disclosed |
| US-4613676-A | PEPTIDES | CIBA-GEIGY CORPORATION (US) | 1986-09-23 | — | — | US | disclosed |
| EP-0184550-A2 | 5-Amino-4-hydroxy valeryl amide derivatives | CIBA-GEIGY AG (CH) | 1986-06-11 | — | — | EP | disclosed |
| EP-0143746-A2 | 5-Amino 4-hydroxy-valeryl-substituted derivatives | CIBA-GEIGY AG (CH) | 1985-06-05 | — | — | EP | disclosed |