Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16749825 | 0.92 | BTK (0.41) | BTKPPARGALOX5 | |
| SCHEMBL16749820 | 0.85 | BTK (0.38) | BTKMCHR1 | |
| SCHEMBL15614922 | 0.83 | BTK (0.37) | BTKKDM4EALDH1A1 | |
| SCHEMBL16749768 | 0.83 | BTK (0.36) | BTKALOX5 | |
| SCHEMBL16749770 | 0.81 | BTK (0.40) | BTKALOX5 | |
| SCHEMBL16749818 | 0.76 | BTK (0.45) | BTKMCHR1 | |
| SCHEMBL15615087 | 0.76 | BTK (0.39) | BTKMCHR1 | |
| SCHEMBL18127520 | 0.76 | SCN9A (0.32) | — | |
| SCHEMBL16749771 | 0.75 | BTK (0.44) | BTKPPARGALOX5 | |
| SCHEMBL15615238 | 0.75 | BTK (0.43) | BTKPPARGKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160289236-A1 | Protein Kinase Inhibitors | PHARMASCIENCE INC. (CA) | 2016-10-06 | — | — | US | disclosed |
| WO-2015074135-A1 | PROTEIN KINASE INHIBITORS | PHARMASCIENCE INC. (CA) | 2015-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160289236-A1 | Protein Kinase Inhibitors | TEC, LCK, SRC | BTK 6/4885PPARG 4142/4885ALOX5 4117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.