Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.77 |
| ▸ | F2 | P00734 | 2/20 | 0.75 |
| ▸ | KLK1 | P06870 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1675026 | 0.95 | F10 (0.80) | F10F2KLK1 | |
| SCHEMBL15911365 | 0.90 | F10 (0.62) | F10F2KLK1 | |
| SCHEMBL1675129 | 0.89 | F10 (0.84) | F10F2KLK1 | |
| SCHEMBL1675071 | 0.89 | F10 (0.84) | F10F2KLK1 | |
| SCHEMBL1675208 | 0.87 | F10 (1.00) | F10F2KLK1 | |
| SCHEMBL1675088 | 0.87 | F10 (1.00) | F10F2KLK1 | |
| SCHEMBL1675103 | 0.86 | F10 (0.84) | F10F2KLK1 | |
| SCHEMBL1675018 | 0.86 | F10 (0.82) | F10F2KLK1 | |
| SCHEMBL1674929 | 0.86 | F10 (1.00) | F10F2KLK1 | |
| SCHEMBL1675507 | 0.86 | F10 (1.00) | F10F2KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4664592-B2 | — | — | 2011-04-06 | — | — | JP | claimed |
| EP-1451185-B1 | INDOLE-2-CARBOXAMIDES AS FACTOR XA INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2014-08-06 | — | — | EP | disclosed |
| US-20090069565-A1 | NEW INDOLE DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-03-12 | — | — | US | disclosed |
| US-20090069565-A1 | NEW INDOLE DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069565-A1 | NEW INDOLE DERIVATIVES AS FACTOR XA INHIBITORS | F12, F5, F2 | F10 10/4885F2 3/4885KLK1 608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.