Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 8/20 | 0.49 |
| ▸ | NOS1 | P29475 | 8/20 | 0.49 |
| ▸ | NOS3 | P29474 | 6/20 | 0.49 |
| ▸ | DDAH1 | O94760 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL5544125 | 1.00 | OTC (0.50) | OTCNOS2NOS1NOS3DDAH1 | |
| Arginine SCHEMBL9754275 | 1.00 | OTC (0.50) | OTCNOS2NOS1NOS3DDAH1 | |
| Arginine SCHEMBL5544129 | 1.00 | OTC (0.50) | OTCNOS2NOS1NOS3DDAH1 | |
| Arginine SCHEMBL1821002 | 1.00 | OTC (0.50) | OTCNOS2NOS1NOS3DDAH1 | |
| Arginine SCHEMBL2787541 | 1.00 | OTC (0.50) | OTCNOS2NOS1NOS3DDAH1 | |
| Arginine SCHEMBL2397458 | 1.00 | OTC (0.50) | OTCNOS2NOS1NOS3DDAH1 | |
| Arginine SCHEMBL5312506 | 1.00 | OTC (0.50) | OTCNOS2NOS1NOS3DDAH1 | |
| Arginine SCHEMBL15323423 | 0.97 | OTC (0.48) | OTCNOS2NOS1NOS3DDAH1 | |
| Arginine SCHEMBL11018148 | 0.97 | OTC (0.48) | OTCNOS2NOS1NOS3DDAH1 | |
| Arginine SCHEMBL15323426 | 0.97 | OTC (0.48) | OTCNOS2NOS1NOS3DDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117789993-B | Establishment and application of gastric cancer prediction model based on tongue fur metabolite | 浙江省肿瘤医院 | 2024-06-11 | — | — | CN | claimed |
| CN-117789993-A | Establishment and application of gastric cancer prediction model based on tongue fur metabolite | 浙江省肿瘤医院 | 2024-03-29 | — | — | CN | claimed |
| WO-2024013258-A1 | PRODUCTION OF CYSTEINE OR CYSTINE FROM SERINE IN FERMENTATION MEDIUM | CYSBIO APS (DK) | 2024-01-18 | — | — | WO | claimed |
| CN-114137226-B | Early diagnosis marker for cerebral infarction, screening method and application thereof, and construction method and application of early diagnosis model for cerebral infarction | 首都师范大学 | 2023-04-28 | — | — | CN | claimed |
| CN-114137226-A | Marker for early diagnosis of cerebral infarction, screening method and application thereof, and construction method and application of model for early diagnosis of cerebral infarction | 首都师范大学 | 2022-03-04 | — | — | CN | claimed |
| CN-110063313-A | A kind of oxygenation bait and preparation method thereof with comprehensive high-tech attracting | 威海猎屋渔具有限公司 | 2019-07-30 | — | — | CN | claimed |
| US-20150293023-A1 | SYSTEMS AND METHODS FOR MEASURING TRANSLATION OF TARGET PROTEINS IN CELLS | ANIMA CELL METROLOGY, INC. | 2015-10-15 | — | — | US | claimed |
| WO-2014026143-A1 | CONJUGATED ANTI-MICROBIAL COMPOUNDS AND CONJUGATED ANTI-CANCER COMPOUNDS AND USES THEREOF | PONO CORPORATION (US) | 2014-02-13 | — | — | WO | claimed |
| US-20120183957-A1 | SYSTEMS AND METHODS FOR MEASURING TRANSLATION OF TARGET PROTEINS IN CELLS | ANIMA CELL METROLOGY, INC. (US) | 2012-07-19 | — | — | US | claimed |
| US-20060275803-A1 | Rat and mouse members of the CRISP family of genes | WYETH (US) | 2006-12-07 | — | — | US | claimed |
| WO-2006119461-A2 | RAT AND MOUSE MEMBERS OF THE CRISP FAMILY OF GENES | WYETH (US) | 2006-11-09 | — | — | WO | claimed |
| EP-1562578-A1 | THERAPEUTIC DELIVERY OF CARBON MONOXIDE TO EXTRACORPOREAL AND ISOLATED ORGANS | Hemocorm Limited (GB) | 2005-08-17 | — | — | EP | claimed |
| WO-2004045598-A1 | THERAPEUTIC DELIVERY OF CARBON MONOXIDE TO EXTRACORPOREAL AND ISOLATED ORGANS | HEMOCORM LIMITED (GB) | 2004-06-03 | — | — | WO | claimed |
| EP-0923287-A4 | NONCLASSICAL PYRROLO 2,3-D]PYRIMIDINE ANTIFOLATES | LILLY CO ELI (US) | 2001-08-01 | — | — | EP | claimed |
| EP-0923287-A1 | NONCLASSICAL PYRROLO 2,3-D]PYRIMIDINE ANTIFOLATES | ELI LILLY AND COMPANY (US) | 1999-06-23 | — | — | EP | claimed |
| WO-1998008382-A1 | NONCLASSICAL PYRROLO[2,3-D]PYRIMIDINE ANTIFOLATES | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | claimed |
| CN-115746110-B | Mutant of transcription control factor LysG and application thereof | 中国科学院天津工业生物技术研究所 | 2024-10-18 | — | — | CN | disclosed |
| US-20240229079-A9 | ENGINEERED TARGET SPECIFIC NUCLEASES | SANGAMO THERAPEUTICS INC (US) | 2024-07-11 | — | — | US | disclosed |
| EP-0199574-A2 | Human tissue plasminogen activator mutants, methods and intermediates therefor, and compositions using such mutants | GENENTECH, INC. (US) | 1986-10-29 | — | — | EP | disclosed |
| WO-1986005208-A1 | POLYPEPTIDES COMPLEMENTARY TO PEPTIDES OR PROTEINS HAVING AN AMINO ACID SEQUENCE OR NUCLEOTIDE CODING SEQUENCE AT LEAST PARTIALLY KNOWN AND METHODS OF DESIGN THEREFOR | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1986-09-12 | — | — | WO | disclosed |