SCHEMBL16757656

SCHEMBL16757656

CC(C)(C)OC(=O)CC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)NCCOCCOCCNC(=O)OC(C)(C)C

nearest known ligand 0.65

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ TLR2 O60603 5/20 0.46
▸ MDM2 Q00987 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ TLR1 Q15399 1/20 0.41
▸ PTPN1 P18031 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16757654 1.00 TLR2 (0.46) TLR2MDM2KMT2ATLR1PTPN1
SCHEMBL31557564 1.00 TLR2 (0.46) TLR2MDM2KMT2ATLR1PTPN1
SCHEMBL18291439 0.96 KMT2A (0.46) TLR2MDM2KMT2ATLR1
SCHEMBL29716713 0.94 TLR2 (0.45) TLR2MDM2PTPN1
SCHEMBL31648943 0.94 TLR2 (0.45) TLR2MDM2PTPN1
SCHEMBL31631998 0.94 TLR2 (0.45) TLR2MDM2PTPN1
SCHEMBL29716733 0.94 TLR2 (0.45) TLR2MDM2PTPN1
SCHEMBL17322760 0.94 TLR2 (0.47) TLR2MDM2PTPN1
SCHEMBL29083314 0.94 TLR2 (0.45) TLR2MDM2PTPN1
SCHEMBL26232024 0.94 TLR2 (0.45) TLR2MDM2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4592275-A2 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE Redwood Bioscience, Inc. (US) 2025-07-30 — — EP disclosed
US-12215080-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCE, INC. (US) 2025-02-04 — — US disclosed
US-20220153696-A1 Hydrazinyl-Pyrrolo Compounds and Methods for Producing a Conjugate ARES CAPITAL CORPORATION, AS COLLATERAL AGENT 2022-05-19 — — US disclosed
US-11180451-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCE, INC. (US) 2021-11-23 — — US disclosed
US-20200317610-A1 Hydrazinyl-Pyrrolo Compounds and Methods for Producing a Conjugate ARES CAPITAL CORPORATION, AS COLLATERAL AGENT 2020-10-08 — — US disclosed
US-10604483-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCE, INC. (US) 2020-03-31 — — US disclosed
US-10464894-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCES, INC. (US) 2019-11-05 — — US disclosed
US-20170049907-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE CATALENT PHARMA SOLUTIONS, LLC 2017-02-23 — — US disclosed
US-9493413-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCE, INC. (US) 2016-11-15 — — US disclosed
EP-3074010-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE Redwood Bioscience, Inc. (US) 2016-10-05 — — EP disclosed
US-20150157736-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE R.P. SCHERER TECHNOLOGIES, LLC 2015-06-11 — — US disclosed
WO-2015081282-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE REDWOOD BIOSCIENCE, INC. (US) 2015-06-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150157736-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE DNPEP, QPCT, PDS5A TLR2 4743/4885MDM2 384/4885KMT2A 1630/4885
US-20220153696-A1 Hydrazinyl-Pyrrolo Compounds and Methods for Producing a Conjugate DNPEP, QPCT, PDS5A TLR2 4743/4885MDM2 384/4885KMT2A 1630/4885
US-20170049907-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE DNPEP, QPCT, PDS5A TLR2 4743/4885MDM2 384/4885KMT2A 1630/4885
US-12215080-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate DNPEP, QPCT, PDS5A TLR2 4743/4885MDM2 384/4885KMT2A 1630/4885
US-11180451-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate DNPEP, QPCT, PDS5A TLR2 4743/4885MDM2 384/4885KMT2A 1630/4885
US-10464894-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate DNPEP, QPCT, PDS5A TLR2 4743/4885MDM2 384/4885KMT2A 1630/4885
US-10604483-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate DNPEP, QPCT, PDS5A TLR2 4743/4885MDM2 384/4885KMT2A 1630/4885
US-20200317610-A1 Hydrazinyl-Pyrrolo Compounds and Methods for Producing a Conjugate DNPEP, QPCT, PDS5A TLR2 4743/4885MDM2 384/4885KMT2A 1630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback