Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.49 |
| ▸ | BRD2 | P25440 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16758584 | 0.90 | BRD4 (0.47) | BRD4BRD2 | |
| SCHEMBL16738863 | 0.81 | BRD4 (0.43) | BRD4BRD2 | |
| SCHEMBL16739005 | 0.81 | BRD4 (0.43) | BRD4BRD2 | |
| SCHEMBL16739019 | 0.81 | BRD4 (0.43) | BRD4BRD2 | |
| SCHEMBL16758597 | 0.76 | BRD4 (0.37) | BRD4 | |
| SCHEMBL16758618 | 0.75 | BRD4 (0.51) | BRD4 | |
| SCHEMBL16758613 | 0.74 | BRD4 (0.41) | BRD4BRD2 | |
| SCHEMBL16738996 | 0.74 | BRD4 (0.41) | BRD4BRD2 | |
| SCHEMBL16738934 | 0.72 | BRD4 (0.40) | BRD4BRD2 | |
| SCHEMBL16739028 | 0.72 | BRD4 (0.40) | BRD4BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015081203-A1 | BICYCLIC HETEROCYCLES AS BET PROTEIN INHIBITORS | INCYTE CORPORATION (US) | 2015-06-04 | — | — | WO | disclosed |