SCHEMBL1676000

SCHEMBL1676000

[CH2][C@@H]1CCCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1892822 1.00
SCHEMBL30821 1.00
Hydrochloric Acid SCHEMBL29090150 0.97
SCHEMBL156910 0.90
SCHEMBL944912 0.90
SCHEMBL943559 0.90
SCHEMBL446149 0.88
SCHEMBL446417 0.88
SCHEMBL28221014 0.88 CYP2D6 (0.37)
SCHEMBL20399494 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3067355-B1 CRYSTALS OF DIAZABICYCLOOCTANE DERIVATIVE AND PRODUCTION METHOD FOR CRYSTALS OF DIAZABICYCLOOCTANE DERIVATIVE MEIJI SEIKA PHARMA CO LTD (JP) 2020-12-16 EP claimed
CN-111153903-A Crystal of diazabicyclooctane derivative, preparation method and application thereof, and pharmaceutical composition 明治制果药业株式会社 2020-05-15 CN claimed
US-10604522-B2 Processes for producing diazabicyclooctane compounds MEIJI SEIKA PHARMA CO., LTD. (JP) 2020-03-31 US claimed
EP-3613741-A1 PREPARATION OF A DIAZABICYCLOOCTANE DERIVATIVE Meiji Seika Pharma Co., Ltd. (JP) 2020-02-26 EP claimed
EP-3613740-A1 PREPARATION OF A DIAZABICYCLOOCTANE DERIVATIVE Meiji Seika Pharma Co., Ltd. (JP) 2020-02-26 EP claimed
US-20190031659-A1 PROCESSES FOR PRODUCING DIAZABICYCLOOCTANE COMPOUNDS MEIJI SEIKA PHARMA CO., LTD. (JP) 2019-01-31 US claimed
US-10131665-B2 Processes for producing diazabicyclooctane compounds MEIJI SEIKA PHARMA CO., LTD. (JP) 2018-11-20 US claimed
US-20160272641-A1 CRYSTALLINE FORMS OF DIAZABICYCLOOCTANE DERIVATIVE AND PRODUCTION PROCESS THEREOF MEIJI SEIKA PHARMA CO., LTD. (JP) 2016-09-22 US claimed
EP-3067355-A1 CRYSTALS OF DIAZABICYCLOOCTANE DERIVATIVE AND PRODUCTION METHOD FOR CRYSTALS OF DIAZABICYCLOOCTANE DERIVATIVE Meiji Seika Pharma Co., Ltd. (JP) 2016-09-14 EP claimed
CN-105612159-A Crystal of diazabicyclooctane derivative and process for producing the same MEIJI SEIKA PHARMA CO LTD 2016-05-25 CN claimed
JP-4673839-B2 2011-04-20 JP claimed
US-7659279-B2 2-{(2S)-2-[({4-[3-Chloro-4-fluoroanilino]-7-methoxyquinazolin-5-yl}oxy)methyl]pyrrolidin-1-yl}-2-oxoethanol; epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors; breast, colorectal and head and neck cancer ASTRAZENECA AB (SE) 2010-02-09 US claimed
EP-1622620-B1 QUINAZOLINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER ASTRAZENECA AB (SE) 2008-02-20 EP claimed
JP-2006525296-A 2006-11-09 JP claimed
US-20060211714-A1 Quinazoline derivatives and their use in the treatment of cancer ASTRAZENECA AB (SE) 2006-09-21 US claimed
EP-1622620-A1 QUINAZOLINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER AstraZeneca AB (SE) 2006-02-08 EP claimed
WO-2004096226-A1 QUINAZOLINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER ASTRAZENECA AB (SE) 2004-11-11 WO claimed
WO-2023205272-A1 PYRAZINAMIDE COMPOUNDS THE GENERAL HOSPITAL CORPORATION (US) 2023-10-26 WO disclosed
US-20030022881-A1 Novel carbapenem derivatives of quarternary salt type MEIJI SEIKA KAISHA, LTD. (JP) 2003-01-30 US disclosed
EP-1251134-A1 NOVEL CARBAPENEM DERIVATIVES OF QUATERNARY SALT TYPE MEIJI SEIKA KAISHA LTD. (JP) 2002-10-23 EP disclosed