Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16769574 | 1.00 | PDE10A (0.48) | PDE10A | |
| SCHEMBL16769570 | 0.86 | PDE10A (0.48) | PDE10A | |
| SCHEMBL16760235 | 0.86 | PDE10A (0.48) | PDE10A | |
| SCHEMBL16760086 | 0.83 | PDE10A (0.56) | PDE10A | |
| SCHEMBL16760025 | 0.83 | PDE10A (0.56) | PDE10A | |
| SCHEMBL16760037 | 0.83 | PDE10A (0.47) | PDE10A | |
| SCHEMBL16760039 | 0.83 | PDE10A (0.47) | PDE10A | |
| SCHEMBL16760027 | 0.82 | PDE10A (0.50) | PDE10A | |
| SCHEMBL2053430 | 0.82 | PDE10A (0.62) | PDE10A | |
| SCHEMBL2053431 | 0.82 | PDE10A (0.62) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074387-A1 | IMIDAZOLE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2016-10-05 | — | — | EP | disclosed |
| WO-2015078836-A1 | IMIDAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2015-06-04 | — | — | WO | disclosed |