Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 20/20 | 0.73 |
| ▸ | KIF5B | P33176 | 10/20 | 0.72 |
| ▸ | KDR | P35968 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16760475 | 0.96 | RET (0.73) | RETKIF5BKDR | |
| SCHEMBL16760526 | 0.90 | RET (0.77) | RETKIF5BKDR | |
| SCHEMBL16760576 | 0.89 | RET (0.73) | RETKIF5BKDR | |
| SCHEMBL16760595 | 0.87 | RET (0.76) | RETKIF5BKDR | |
| SCHEMBL16760527 | 0.87 | RET (0.83) | RETKIF5BKDR | |
| SCHEMBL16760392 | 0.87 | RET (0.72) | RETKIF5BKDR | |
| SCHEMBL16760603 | 0.86 | RET (0.82) | RETKIF5BKDR | |
| SCHEMBL16760548 | 0.85 | RET (1.00) | RETKIF5BKDR | |
| SCHEMBL16760560 | 0.85 | RET (0.77) | RETKIF5BKDR | |
| SCHEMBL16760519 | 0.84 | RET (0.73) | RETKIF5BKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015079251-A1 | QUINAZOLINE COMPOUNDS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2015-06-04 | — | — | WO | disclosed |