Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 15/20 | 1.00 |
| ▸ | KIF5B | P33176 | 11/20 | 0.74 |
| ▸ | KDR | P35968 | 11/20 | 0.74 |
| ▸ | EGFR | P00533 | 4/20 | 0.69 |
| ▸ | FLT1 | P17948 | 3/20 | 0.63 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.61 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.58 |
| ▸ | CDK2 | P24941 | 1/20 | 0.58 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.58 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.58 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16760370 | 0.85 | RET (1.00) | RETKIF5BKDREGFRFLT1 | |
| SCHEMBL5864594 | 0.85 | RET (1.00) | RETKIF5BKDREGFRFLT1 | |
| SCHEMBL7076160 | 0.85 | RET (1.00) | RETKIF5BKDREGFRFLT1 | |
| SCHEMBL16785515 | 0.84 | RET (1.00) | RETKIF5BKDREGFRFLT1 | |
| SCHEMBL16760418 | 0.84 | RET (1.00) | RETKIF5BKDREGFRFLT1 | |
| Hydrochloric Acid SCHEMBL16760376 | 0.83 | RET (0.98) | RETKIF5BKDREGFRFLT1 | |
| SCHEMBL16760410 | 0.83 | RET (1.00) | RETKIF5BKDREGFRFLT1 | |
| Hydrochloric Acid SCHEMBL16760380 | 0.82 | RET (0.98) | RETKIF5BKDREGFRFLT1 | |
| SCHEMBL5864606 | 0.81 | EGFR (1.00) | RETKIF5BKDREGFRFLT1 | |
| SCHEMBL22427658 | 0.81 | RET (0.68) | RETKIF5BKDREGFRFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015079251-A1 | QUINAZOLINE COMPOUNDS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2015-06-04 | — | — | WO | disclosed |