Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 20/20 | 1.00 |
| ▸ | KIF5B | P33176 | 10/20 | 0.90 |
| ▸ | KDR | P35968 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16760496 | 0.99 | RET (1.00) | RETKIF5BKDR | |
| SCHEMBL16760559 | 0.99 | RET (1.00) | RETKIF5BKDR | |
| SCHEMBL16760355 | 0.98 | RET (0.97) | RETKIF5BKDR | |
| SCHEMBL16760444 | 0.96 | RET (1.00) | RETKIF5B | |
| SCHEMBL16760449 | 0.95 | RET (1.00) | RETKIF5B | |
| SCHEMBL16760386 | 0.95 | RET (1.00) | RETKIF5B | |
| SCHEMBL16760425 | 0.94 | RET (0.94) | RETKIF5BKDR | |
| SCHEMBL16760439 | 0.94 | RET (1.00) | RETKIF5BKDR | |
| SCHEMBL16760371 | 0.94 | RET (0.97) | RETKIF5B | |
| SCHEMBL16760382 | 0.93 | RET (0.94) | RETKIF5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015079251-A1 | QUINAZOLINE COMPOUNDS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2015-06-04 | — | — | WO | claimed |
| WO-2015079251-A1 | QUINAZOLINE COMPOUNDS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2015-06-04 | — | — | WO | disclosed |