Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 20/20 | 0.72 |
| ▸ | KIF5B | P33176 | 9/20 | 0.72 |
| ▸ | KDR | P35968 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16760558 | 0.88 | RET (0.77) | RETKIF5BKDR | |
| SCHEMBL16760537 | 0.87 | RET (0.69) | RETKIF5BKDR | |
| SCHEMBL16760413 | 0.86 | RET (0.70) | RETKIF5BKDR | |
| SCHEMBL16760597 | 0.86 | RET (0.77) | RETKIF5BKDR | |
| SCHEMBL16760395 | 0.85 | RET (0.81) | RETKIF5BKDR | |
| SCHEMBL16760596 | 0.85 | RET (0.78) | RETKIF5BKDR | |
| SCHEMBL29571310 | 0.85 | RET (1.00) | RETKIF5BKDR | |
| SCHEMBL20399516 | 0.85 | RET (1.00) | RETKIF5BKDR | |
| Hydrochloric Acid SCHEMBL16760467 | 0.84 | RET (0.98) | RETKIF5BKDR | |
| SCHEMBL16760557 | 0.83 | RET (0.74) | RETKIF5BKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015079251-A1 | QUINAZOLINE COMPOUNDS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2015-06-04 | — | — | WO | disclosed |