Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL14759095 | 1.00 | TSHR (0.56) | TSHRALDH1A1CYP3A4CES2MEN1 | |
| Acetic Acid SCHEMBL1996435 | 1.00 | TSHR (0.56) | TSHRALDH1A1CYP3A4CES2MEN1 | |
| Acetic Acid SCHEMBL29287060 | 1.00 | TSHR (0.56) | TSHRALDH1A1CYP3A4CES2MEN1 | |
| Acetic Acid SCHEMBL4617603 | 1.00 | TSHR (0.56) | TSHRALDH1A1CYP3A4CES2MEN1 | |
| Acetic Acid SCHEMBL9616198 | 0.97 | TSHR (0.59) | TSHRALDH1A1CYP3A4CES2MEN1 | |
| Acetic Acid SCHEMBL28723481 | 0.97 | TSHR (0.59) | TSHRALDH1A1CYP3A4CES2MEN1 | |
| Acetic Acid SCHEMBL37245 | 0.97 | TSHR (0.59) | TSHRALDH1A1CYP3A4CES2MEN1 | |
| Acetic Acid SCHEMBL4208068 | 0.95 | TSHR (0.52) | TSHRALDH1A1CYP3A4CES2MEN1 | |
| Acetic Acid SCHEMBL27879900 | 0.95 | TSHR (0.56) | TSHRALDH1A1CYP3A4CES2MEN1 | |
| Acetic Acid SCHEMBL28054997 | 0.95 | TSHR (0.56) | TSHRALDH1A1CYP3A4CES2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2881442-B1 | POLYISOCYANATE COMPOSITION, SOLAR CELL MEMBER COVERING MATERIAL, SOLAR CELL MEMBER WITH COVERING LAYER, MICROCAPSULE, AND INK BINDER | MITSUI CHEMICALS INC (JP) | 2018-09-05 | — | — | EP | disclosed |
| US-9822212-B2 | Polyisocyanate composition, solar cell member covering material, solar cell member with cover layer, microcapsule, and binder for ink | MITSUI CHEMICALS, INC. (JP) | 2017-11-21 | — | — | US | disclosed |
| US-9612535-B2 | Pattern forming method, electron beam- or extreme ultraviolet-sensitive resin composition, resist film using the same, method of manufacturing electronic device, and electronic device | FUJIFILM CORPORATION (JP) | 2017-04-04 | — | — | US | disclosed |
| US-20150370170-A1 | PATTERN FORMING METHOD, ELECTRON BEAM- OR EXTREME ULTRAVIOLET-SENSITIVE RESIN COMPOSITION, RESIST FILM USING THE SAME, METHOD OF MANUFACTURING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE | FUJIFILM CORPORATION (JP) | 2015-12-24 | — | — | US | disclosed |
| US-20150183922-A1 | POLYISOCYANATE COMPOSITION, SOLAR CELL MEMBER COVERING MATERIAL, SOLAR CELL MEMBER WITH COVER LAYER, MICROCAPSULE, AND BINDER FOR INK | MITSUI CHEMICALS, INC. (JP) | 2015-07-02 | — | — | US | disclosed |
| EP-2881442-A1 | POLYISOCYANATE COMPOSITION, SOLAR CELL MEMBER COVERING MATERIAL, SOLAR CELL MEMBER WITH COVERING LAYER, MICROCAPSULE, AND INK BINDER | Mitsui Chemicals, Inc. (JP) | 2015-06-10 | — | — | EP | disclosed |