Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21715244 | 1.00 | CA1 (0.54) | CA1CA2FOLH1PRSS1PRSS2 | |
| SCHEMBL16762202 | 0.92 | FOLH1 (0.52) | CA1CA2FOLH1MMP2MMP9 | |
| SCHEMBL28820366 | 0.89 | SIRT2 (0.49) | CA1CA2FOLH1PTGER4 | |
| SCHEMBL31277511 | 0.89 | SIRT2 (0.51) | FOLH1 | |
| SCHEMBL21543891 | 0.89 | SIRT2 (0.51) | FOLH1 | |
| SCHEMBL21543552 | 0.87 | MAPT (0.57) | FOLH1 | |
| SCHEMBL16762087 | 0.87 | FOLH1 (0.48) | FOLH1 | |
| SCHEMBL16762160 | 0.85 | FOLH1 (0.46) | CA1CA2FOLH1PRSS1PRSS2 | |
| SCHEMBL16761989 | 0.85 | FOLH1 (0.46) | CA1CA2FOLH1PRSS1PRSS2 | |
| SCHEMBL15249565 | 0.85 | DPP8 (0.48) | FOLH1MMP2MMP9DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2881392-A1 | Agonists that enhance binding of integrin-expressing cells to integrin receptors | Texas Heart Institute (US) | 2015-06-10 | — | — | EP | disclosed |