Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 17/20 | 0.65 |
| ▸ | EGFR | P00533 | 3/20 | 0.65 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.65 |
| ▸ | KDR | P35968 | 3/20 | 0.54 |
| ▸ | RET | P07949 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2960561 | 0.92 | IGF1R (0.60) | IGF1REGFRERBB2KDRRET | |
| SCHEMBL2958098 | 0.90 | IGF1R (0.69) | IGF1REGFRERBB2 | |
| SCHEMBL2959425 | 0.89 | IGF1R (0.63) | IGF1REGFRERBB2 | |
| SCHEMBL2956438 | 0.87 | IGF1R (0.60) | IGF1REGFRERBB2KDR | |
| SCHEMBL2965040 | 0.87 | IGF1R (0.60) | IGF1REGFRERBB2KDR | |
| SCHEMBL2956433 | 0.87 | IGF1R (0.60) | IGF1REGFRERBB2KDR | |
| SCHEMBL2953928 | 0.87 | IGF1R (0.70) | IGF1REGFRERBB2 | |
| SCHEMBL2963721 | 0.87 | IGF1R (0.70) | IGF1REGFRERBB2 | |
| SCHEMBL2953930 | 0.87 | IGF1R (0.70) | IGF1REGFRERBB2 | |
| SCHEMBL2967474 | 0.87 | IGF1R (0.76) | IGF1REGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973917-B1 | PROTEIN KINASE INHIBITORS | ABBVIE INC (US) | 2015-06-10 | — | — | EP | claimed |