Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2955782 | 0.90 | F2 (0.63) | F2SMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL9476190 | 0.84 | F2 (0.57) | F2SMN1; SMN2ALDH1A1KMT2AHGFAC | |
| SCHEMBL29787109 | 0.83 | F2 (0.60) | F2SMN1; SMN2ALDH1A1HGFACCYP2C9 | |
| SCHEMBL916164 | 0.83 | F2 (0.60) | F2SMN1; SMN2ALDH1A1HGFACCYP2C9 | |
| SCHEMBL7929197 | 0.83 | F2 (0.63) | F2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL12919991 | 0.83 | F2 (0.56) | F2SMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL4260502 | 0.83 | F2 (0.56) | F2SMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL28472004 | 0.82 | F2 (0.58) | F2SMN1; SMN2ALDH1A1HGFACCYP2C9 | |
| SCHEMBL11195246 | 0.81 | F2 (0.61) | F2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7671999 | 0.81 | TSHR (0.55) | F2ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9321762-B2 | Quinazoline compounds, method for preparing the same and use thereof | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2016-04-26 | — | — | US | disclosed |
| US-20150158854-A1 | QUINAZOLINE COMPOUNDS, METHOD FOR PREPARING THE SAME AND USE THEREOF | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2015-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150158854-A1 | QUINAZOLINE COMPOUNDS, METHOD FOR PREPARING THE SAME AND USE THEREOF | PKN2, CNKSR1, ABL1 | F2 1363/4885SMN1; SMN2 2017/4885ALDH1A1 4556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.