SCHEMBL16765710

SCHEMBL16765710

CCCCCCC1CCCC1(C)O

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.40
EPHX1 P07099 1/20 0.37
ALDH1A1 P00352 1/20 0.35
S1PR1 P21453 3/20 0.34
S1PR3 Q99500 3/20 0.34
S1PR2 O95136 2/20 0.33
S1PR4 O95977 2/20 0.33
S1PR5 Q9H228 2/20 0.33
LIPA P38571 1/20 0.33
LSS P48449 2/20 0.33
ALOX5 P09917 1/20 0.33
CYP1A2 P05177 2/20 0.32
CYP19A1 P11511 3/20 0.32
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
CYP2C19 P33261 1/20 0.32
GBA1 P04062 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16765708 1.00 TDP1 (0.40) TDP1EPHX1ALDH1A1S1PR1S1PR3
SCHEMBL16765715 0.98 TDP1 (0.41) TDP1EPHX1ALDH1A1S1PR1S1PR3
Water SCHEMBL28036000 0.93 EPHX1 (0.35) TDP1EPHX1ALDH1A1S1PR1S1PR3
SCHEMBL16767016 0.92 TDP1 (0.45) TDP1CYP1A2
SCHEMBL19263000 0.92 TDP1 (0.45) TDP1CYP1A2
Water SCHEMBL28822891 0.91 TDP1 (0.36) TDP1EPHX1ALDH1A1S1PR1S1PR3
SCHEMBL548102 0.89 EPHX1 (0.39) EPHX1ALDH1A1S1PR1S1PR3S1PR2
SCHEMBL16765904 0.84 CA1 (0.34) TDP1CYP19A1
SCHEMBL16766423 0.80 TDP1 (0.39) TDP1EPHX1ALDH1A1S1PR1S1PR3
SCHEMBL16766402 0.80 TDP1 (0.39) TDP1EPHX1ALDH1A1S1PR1S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104710283-B Cyclopentanol compound 国际香料和香精公司 2019-06-11 CN disclosed
US-9701925-B2 Cyclopentanol compounds INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2017-07-11 US disclosed
US-20160160152-A1 NOVEL CYCLOPENTANOL COMPOUNDS INTERNATIONAL FLAVORS & FRAGRANCES INC. 2016-06-09 US disclosed
US-9290718-B2 Cyclopentanol compounds INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2016-03-22 US disclosed
EP-2902468-A2 Novel cyclopentanol compounds International Flavors & Fragrances Inc. (US) 2015-08-05 EP disclosed
CN-104710283-A Novel cyclopentanol compounds INT FLAVORS & FRAGRANCES INC 2015-06-17 CN disclosed
US-20150159118-A1 NOVEL CYCLOPENTANOL COMPOUNDS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2015-06-11 US disclosed