Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16768640 | 0.79 | ANPEP (0.41) | NPSR1ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL22810500 | 0.76 | NPSR1 (0.36) | NPSR1SMN1; SMN2ALDH1A1MAPTGAA | |
| SCHEMBL18674517 | 0.74 | KDM1A (0.48) | ALDH1A1MEN1KMT2ATSHRPOLB | |
| SCHEMBL18677976 | 0.74 | KDM1A (0.48) | ALDH1A1MEN1KMT2ATSHRPOLB | |
| SCHEMBL17345944 | 0.74 | KDM1A (0.48) | ALDH1A1MEN1KMT2ATSHRPOLB | |
| SCHEMBL18677975 | 0.74 | KDM1A (0.48) | ALDH1A1MEN1KMT2ATSHRPOLB | |
| SCHEMBL23783602 | 0.69 | PSEN1 (0.41) | SSTR3SMN1; SMN2ALDH1A1KDM4EPDCD1 | |
| SCHEMBL30556728 | 0.68 | GAA (0.65) | NPSR1ALDH1A1MAPTGAAMEN1 | |
| SCHEMBL282957 | 0.68 | PSEN1 (0.52) | NPSR1SMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL282958 | 0.68 | PSEN1 (0.52) | NPSR1SMN1; SMN2ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9597673-B2 | Iron catalysts with unsymmetrical PNN'P ligands | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2017-03-21 | — | — | US | disclosed |
| US-9597673-B2 | Iron catalysts with unsymmetrical PNN'P ligands | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2017-03-21 | — | — | US | disclosed |
| US-20150151289-A1 | IRON CATALYSTS WITH UNSYMMETRICAL PNN'P LIGANDS | GOVERING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2015-06-04 | — | — | US | disclosed |
| US-20150151289-A1 | IRON CATALYSTS WITH UNSYMMETRICAL PNN'P LIGANDS | GOVERING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150151289-A1 | IRON CATALYSTS WITH UNSYMMETRICAL PNN'P LIGANDS | PNN, NCL, IDH2 | SSTR3 3484/4885NPSR1 1400/4885SMN1; SMN2 2527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.