Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 5/20 | 0.32 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22810501 | 1.00 | KDM1A (0.35) | KDM1AMAOAMAOBALDH1A1ANPEP | |
| SCHEMBL16768617 | 0.75 | KDM1A (0.32) | KDM1AMAOAMAOBALDH1A1KDM4E | |
| SCHEMBL17345950 | 0.74 | KDM1A (0.50) | KDM1AMAOAALDH1A1 | |
| SCHEMBL18674530 | 0.74 | KDM1A (0.50) | KDM1AMAOAALDH1A1 | |
| SCHEMBL6685748 | 0.72 | KDM1A (0.50) | KDM1AMAOAMAOBSSTR3CDK1 | |
| SCHEMBL8038053 | 0.72 | KDM1A (0.50) | KDM1AMAOAMAOBSSTR3CDK1 | |
| SCHEMBL11562884 | 0.72 | KDM1A (0.50) | KDM1AMAOAMAOBSSTR3CDK1 | |
| SCHEMBL12339369 | 0.72 | ANPEP (0.48) | ANPEPERAP2PIM1 | |
| SCHEMBL14970025 | 0.72 | ANPEP (0.48) | ANPEPERAP2PIM1 | |
| SCHEMBL12339368 | 0.72 | ANPEP (0.48) | ANPEPERAP2PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9597673-B2 | Iron catalysts with unsymmetrical PNN'P ligands | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2017-03-21 | — | — | US | disclosed |
| US-9597673-B2 | Iron catalysts with unsymmetrical PNN'P ligands | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2017-03-21 | — | — | US | disclosed |
| US-20150151289-A1 | IRON CATALYSTS WITH UNSYMMETRICAL PNN'P LIGANDS | GOVERING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2015-06-04 | — | — | US | disclosed |
| US-20150151289-A1 | IRON CATALYSTS WITH UNSYMMETRICAL PNN'P LIGANDS | GOVERING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150151289-A1 | IRON CATALYSTS WITH UNSYMMETRICAL PNN'P LIGANDS | PNN, NCL, IDH2 | KDM1A 4079/4885MAOA 734/4885MAOB 694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.