Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1713096 | 0.83 | NR1H2 (0.49) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL17733829 | 0.78 | SMN1; SMN2 (0.41) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL2153590 | 0.74 | HPGD (0.57) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL2153593 | 0.74 | HPGD (0.57) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL14348065 | 0.74 | HPGD (0.57) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8313236 | 0.72 | CHRM2 (0.35) | NR1H2 | |
| SCHEMBL12631837 | 0.72 | MEN1 (0.60) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL14348057 | 0.72 | MEN1 (0.60) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL30793858 | 0.71 | HPGD (0.57) | HPGDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL13885510 | 0.71 | NR1H2 (0.32) | NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2345629-B1 | FLUORENE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | JAPAN TOBACCO INC (JP) | 2015-06-03 | — | — | EP | disclosed |