Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15792164 | 0.89 | HRH3 (0.38) | HRH3SLC6A2ACKR3PDK1DRD4 | |
| SCHEMBL9935682 | 0.88 | HRH3 (0.39) | HRH3SLC6A2ACKR3PDK1EPHX1 | |
| Water SCHEMBL1358132 | 0.87 | HRH3 (0.37) | HRH3SLC6A2ACKR3PDK1DRD4 | |
| SCHEMBL9935790 | 0.84 | HRH3 (0.41) | HRH3SLC6A2ACKR3PDK1EPHX1 | |
| SCHEMBL23710267 | 0.83 | EPHX1 (0.47) | HRH3SLC6A2ACKR3PDK1EPHX1 | |
| SCHEMBL29156205 | 0.81 | EPHX1 (0.55) | HRH3SLC6A2EPHX1 | |
| Bromide SCHEMBL28105124 | 0.81 | EPHX1 (0.46) | HRH3SLC6A2ACKR3PDK1EPHX1 | |
| Hydrochloric Acid SCHEMBL28608172 | 0.81 | EPHX1 (0.46) | HRH3SLC6A2ACKR3PDK1EPHX1 | |
| Iodide SCHEMBL28167228 | 0.81 | EPHX1 (0.46) | HRH3SLC6A2ACKR3PDK1EPHX1 | |
| SCHEMBL1183098 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9340538-B2 | Dihydropyrimidine compounds and their application in pharmaceuticals | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-05-17 | — | — | US | disclosed |
| US-20150152096-A1 | DIHYDROPYRIMIDINE COMPOUNDS AND THEIR APPLICATION IN PHARMACEUTICALS | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152096-A1 | DIHYDROPYRIMIDINE COMPOUNDS AND THEIR APPLICATION IN PHARMACEUTICALS | DPYD, SLC10A1, HPRT1 | HRH3 1555/4885SLC6A2 535/4885ACKR3 1897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.