Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 3/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20553917 | 0.96 | ACE (0.56) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL20553920 | 0.96 | ACE (0.56) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL30288027 | 0.95 | ACE (0.51) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL29564354 | 0.95 | ACE (0.51) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL30288039 | 0.95 | ACE (0.51) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL30123099 | 0.90 | MME (0.46) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL6809797 | 0.89 | ACE (0.56) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL22969994 | 0.89 | ACE (0.56) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL7072854 | 0.89 | ACE (0.56) | ACEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL16770240 | 0.89 | ACE (0.56) | ACEKDM4EMAPTTHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015081117-A2 | THERAPEUTIC METAL COMPLEXES | ECHOGEN, INC. (US) | 2015-06-04 | — | — | WO | disclosed |