Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16770731 | 1.00 | PPARA (0.32) | PPARASCN9ANPSR1S1PR3ALDH1A1 | |
| SCHEMBL16771234 | 0.83 | SCN9A (0.33) | SCN9AS1PR3 | |
| SCHEMBL17062222 | 0.81 | SCN9A (0.37) | SCN9AS1PR3 | |
| SCHEMBL17069230 | 0.80 | SCN9A (0.32) | SCN9AS1PR3 | |
| SCHEMBL17069222 | 0.80 | SCN9A (0.32) | SCN9AS1PR3 | |
| SCHEMBL18400082 | 0.73 | OPRL1 (0.32) | — | |
| SCHEMBL28209656 | 0.70 | PDE10A (0.38) | — | |
| SCHEMBL23159261 | 0.69 | — | — | |
| SCHEMBL4585034 | 0.65 | CCR1 (0.37) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL22576353 | 0.65 | MAPK9 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015078374-A1 | SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2015-06-04 | — | — | WO | disclosed |