⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrazole SCHEMBL23387532 | 1.00 | — | — | |
| Pyrazole SCHEMBL17102294 | 0.97 | — | — | |
| Pyrazole SCHEMBL30626480 | 0.96 | — | — | |
| Pyrazole SCHEMBL30854861 | 0.96 | — | — | |
| Pyrazole SCHEMBL7671561 | 0.96 | — | — | |
| Pyrazole SCHEMBL5664483 | 0.96 | — | — | |
| Pyrazole SCHEMBL1384 | 0.96 | — | — | |
| Pyrazole SCHEMBL11537298 | 0.93 | — | — | |
| Pyrazole SCHEMBL3285574 | 0.93 | — | — | |
| Pyrazole SCHEMBL6394854 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 557 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878464-A | Preparation method of aminated formamido pyrazole derivative compound | 常州优凯美医药科技有限公司 | 2024-11-01 | — | — | CN | claimed |
| CN-117983154-A | Production system and production method for continuously synthesizing water-insoluble azo dye in flowing mode in all-water system | 大连理工大学 | 2024-05-07 | — | — | CN | claimed |
| CN-220824514-U | Pyrazoleamine multilayer filter equipment | 怀仁诚隆化工科技有限公司 | 2024-04-23 | — | — | CN | claimed |
| CN-220454106-U | Pyrazoleamine material drying device | 怀仁诚隆化工科技有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-117164517-A | Phenoxybenzamide derivative containing substituted pyrazole, preparation method and application thereof | 西北农林科技大学 | 2023-12-05 | — | — | CN | claimed |
| CN-107540666-B | Benzofuran pyrazole amine protein kinase inhibitor | 杭州雷索药业有限公司 | 2023-03-24 | — | — | CN | claimed |
| EP-4009972-A1 | \"TRPSWITCH\" - A STEP FUNCTION CHEMO-OPTOGENETIC LIGAND | University of Utah Research Foundation (US) | 2022-06-15 | — | — | EP | claimed |
| WO-2021030165-A1 | \"TRPSWITCH\" − A STEP FUNCTION CHEMO-OPTOGENETIC LIGAND | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2021-02-18 | — | — | WO | claimed |
| CN-107540616-B | Preparation method of high-enantioselectivity pyrazole amine compound | 河南大学 | 2020-07-31 | — | — | CN | claimed |
| CN-109293666-B | 7-pyrazolidine- [1,2,4] triazolo [1,5-a ] pyrimidine compound and preparation method and application thereof | 郑州大学 | 2020-06-02 | — | — | CN | claimed |
| WO-2007049041-A1 | 4- (3-AMINOPYRAZOLE) PYRIMIDINE DERIVATIVES FOR USE AS TYROSINE KINASE INHIBITORS IN THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2007-05-03 | — | — | WO | claimed |
| CN-1946395-A | 1H-thieno [2, 3-c ] pyrazole derivatives useful as kinase inhibitors | PHARMACIA ITALIA SPA (IT) | 2007-04-11 | — | — | CN | claimed |
| CN-1905884-A | Pyrazole derivatives as inhibitors of receptor tyrosyne kinases | ASTRAZENECA AB (SE) | 2007-01-31 | — | — | CN | claimed |
| WO-2006123113-A2 | PYRAZOLYLAMINOPYRIMIDINE DERIVATIVES USEFUL AS TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2006-11-23 | — | — | WO | claimed |
| WO-2006117560-A1 | PYRAZOLYL-AMINO- SUBSTITUTED PYRIMIDINES AND THEIR USE IN THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2006-11-09 | — | — | WO | claimed |
| EP-1686999-A1 | PYRAZOLE DERIVATIVES AS INHIBITORS OF RECEPTOR TYROSINE KINASES | AstraZeneca AB (SE) | 2006-08-09 | — | — | EP | claimed |
| WO-2005049033-A1 | PYRAZOLE DERIVATIVES AS INHIBITORS OF RECEPTOR TYROSYNE KINASES | ASTRAZENECA AB (SE) | 2005-06-02 | — | — | WO | claimed |
| CN-1507447-A | Substituted pyrazolopyrimidines and thiazolopyrimidines | — | 2004-06-23 | — | — | CN | claimed |
| CN-1325398-A | Pyrazolopyrimidinone derivatives for the treatment of impotence | DONG A PHARM CO LTD (KR) | 2001-12-05 | — | — | CN | claimed |
| CN-1259013-A | Herbicidal compositions | ISAGRO RICERCA SRL (IT) | 2000-07-05 | — | — | CN | claimed |