Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 19/20 | 0.40 |
| ▸ | BRD2 | P25440 | 2/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.40 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.40 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 3/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16784528 | 0.90 | BRD4 (0.41) | BRD4BRD2TRIM24BRD3BRDT | |
| SCHEMBL16738963 | 0.87 | BRD4 (0.49) | BRD4BRD2TRIM24BRD3BRDT | |
| SCHEMBL16738961 | 0.79 | BRD4 (0.64) | BRD4BRD2TRIM24BRD3BRDT | |
| SCHEMBL16739021 | 0.78 | BRD4 (0.45) | BRD4BRD2TRIM24BRD3BRDT | |
| SCHEMBL16738858 | 0.77 | BRD4 (0.48) | BRD4BRD2TRIM24BRD3BRDT | |
| SCHEMBL16739048 | 0.76 | BRD4 (0.50) | BRD4BRD2TRIM24BRD3BRDT | |
| SCHEMBL16738727 | 0.73 | BRD4 (0.52) | BRD4BRD2TRIM24BRD3BRDT | |
| SCHEMBL16758612 | 0.73 | BRD4 (0.47) | BRD4 | |
| SCHEMBL16738887 | 0.72 | BRD4 (0.46) | BRD4BRD2TRIM24BRD3BRDT | |
| SCHEMBL16738925 | 0.72 | BRD4 (0.47) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015081203-A1 | BICYCLIC HETEROCYCLES AS BET PROTEIN INHIBITORS | INCYTE CORPORATION (US) | 2015-06-04 | — | — | WO | disclosed |