Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.71 |
| ▸ | BRD2 | P25440 | 3/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16758642 | 0.93 | BRD4 (0.70) | BRD4BRD2 | |
| SCHEMBL16738906 | 0.91 | BRD4 (0.69) | BRD4BRD2 | |
| SCHEMBL16738898 | 0.91 | BRD4 (0.69) | BRD4BRD2 | |
| SCHEMBL16739056 | 0.88 | BRD4 (0.66) | BRD4BRD2 | |
| SCHEMBL16738951 | 0.87 | BRD4 (0.85) | BRD4BRD2 | |
| SCHEMBL18391632 | 0.86 | BRD4 (0.73) | BRD4BRD2 | |
| SCHEMBL16758643 | 0.85 | BRD4 (0.66) | BRD4BRD2 | |
| Trifluoroacetic Acid SCHEMBL16738905 | 0.84 | BRD4 (0.78) | BRD4BRD2 | |
| SCHEMBL16738919 | 0.83 | BRD4 (1.00) | BRD4BRD2 | |
| SCHEMBL16739039 | 0.83 | BRD4 (1.00) | BRD4BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015081203-A1 | BICYCLIC HETEROCYCLES AS BET PROTEIN INHIBITORS | INCYTE CORPORATION (US) | 2015-06-04 | — | — | WO | disclosed |