Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 9/20 | 0.67 |
| ▸ | PTPRC | P08575 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CDC25A | P30304 | 1/20 | 0.55 |
| ▸ | CDC25B | P30305 | 1/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.49 |
| ▸ | CSNK2A3 | Q8NEV1 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2901286 | 0.81 | HSD17B10 (0.53) | TTRKMT2AMEN1MAPTTDP1 | |
| SCHEMBL30610011 | 0.81 | TTR (1.00) | TTRPTPRCKMT2AMEN1MAPT | |
| SCHEMBL123492 | 0.81 | TTR (1.00) | TTRPTPRCKMT2AMEN1MAPT | |
| SCHEMBL3976640 | 0.80 | TTR (0.73) | TTRPTPRCKMT2AMEN1MAPT | |
| SCHEMBL31436146 | 0.80 | TTR (0.73) | TTRPTPRCKMT2AMEN1MAPT | |
| SCHEMBL28446002 | 0.79 | TTR (0.96) | TTRPTPRCKMT2AMEN1MAPT | |
| SCHEMBL6261915 | 0.79 | PTPRC (1.00) | TTRPTPRCKMT2AMEN1MAPT | |
| SCHEMBL292802 | 0.79 | TTR (0.96) | TTRPTPRCKMT2AMEN1MAPT | |
| SCHEMBL29917994 | 0.79 | TTR (0.96) | TTRPTPRCKMT2AMEN1MAPT | |
| SCHEMBL11877439 | 0.79 | TTR (0.96) | TTRPTPRCKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9052324-B2 | Compounds and assays for controlling Wnt activity | ENZO BIOCHEM, INC. (US) | 2015-06-09 | — | — | US | disclosed |