Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 10/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 8/20 | 0.51 |
| ▸ | RXRA | P19793 | 8/20 | 0.42 |
| ▸ | PTGES | O14684 | 3/20 | 0.36 |
| ▸ | AR | P10275 | 4/20 | 0.34 |
| ▸ | BCL2 | P10415 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679025 | 0.88 | NR1H2 (0.52) | NR1H2NR1H3RXRA | |
| SCHEMBL1678622 | 0.87 | NR1H2 (0.51) | NR1H2NR1H3RXRA | |
| SCHEMBL1679181 | 0.87 | NR1H2 (0.51) | NR1H2NR1H3RXRAAR | |
| SCHEMBL1679550 | 0.85 | NR1H2 (0.49) | NR1H2NR1H3RXRA | |
| SCHEMBL1679552 | 0.85 | NR1H2 (0.49) | NR1H2NR1H3RXRA | |
| SCHEMBL1679270 | 0.85 | NR1H2 (0.44) | NR1H2NR1H3RXRAAR | |
| SCHEMBL1678027 | 0.83 | NR1H2 (0.75) | NR1H2NR1H3RXRAPTGES | |
| SCHEMBL5067204 | 0.81 | NR1H2 (0.68) | NR1H2NR1H3RXRA | |
| SCHEMBL1679162 | 0.81 | NR1H2 (0.50) | NR1H2NR1H3RXRA | |
| SCHEMBL1679168 | 0.81 | NR1H2 (0.50) | NR1H2NR1H3RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7923573-B2 | Benzene compound having 2 or more substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-12 | — | — | US | disclosed |
| US-20080004301-A1 | Benzene Compound Having 2 or More Substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004301-A1 | Benzene Compound Having 2 or More Substituents | NR1H2, NR1H3, NCOR2 | NR1H2 1/4885NR1H3 2/4885RXRA 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.