Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.71 |
| ▸ | NPC1 | O15118 | 11/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | RAB9A | P51151 | 9/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.60 |
| ▸ | AHR | P35869 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | CASP1 | P29466 | 2/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16794821 | 0.84 | MAPT (0.77) | MAPTNPC1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL429754 | 0.84 | MAPT (1.00) | MAPTNPC1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL7843704 | 0.80 | SMN1; SMN2 (0.74) | MAPTNPC1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL14172644 | 0.79 | NPC1 (0.44) | MAPTNPC1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL13335658 | 0.79 | NPC1 (0.56) | MAPTNPC1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL14172704 | 0.79 | NPC1 (0.44) | MAPTNPC1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL1869991 | 0.75 | NPC1 (1.00) | MAPTNPC1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL30979841 | 0.75 | MAPT (1.00) | MAPTNPC1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL30979845 | 0.75 | MAPT (1.00) | MAPTNPC1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL9720114 | 0.75 | MAPT (1.00) | MAPTNPC1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015088564-A1 | P2X4 RECEPTOR MODULATING COMPOUNDS | SUNOVION PHARMACEUTICALS INC. (US) | 2015-06-18 | — | — | WO | disclosed |