Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL17061168 | 0.98 | CYP3A4 (0.57) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL6260735 | 0.87 | TDP1 (0.50) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL29024165 | 0.85 | CYP3A4 (0.60) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL27745065 | 0.85 | CYP3A4 (0.48) | CYP3A4TDP1ESR1ESR2KDM4E | |
| Propane SCHEMBL27796760 | 0.84 | CYP3A4 (0.75) | CYP3A4TDP1ESR1ESR2KDM4E | |
| Propane SCHEMBL28233649 | 0.84 | CYP3A4 (0.75) | CYP3A4TDP1ESR1ESR2KDM4E | |
| Ether SCHEMBL1131751 | 0.83 | CYP3A4 (0.41) | CYP3A4TDP1ESR1ESR2KDM4E | |
| Butane SCHEMBL27989459 | 0.81 | CYP3A4 (0.71) | CYP3A4TDP1ESR1ESR2KDM4E | |
| Butane SCHEMBL28244852 | 0.81 | CYP3A4 (0.71) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL8845876 | 0.81 | CYP3A4 (0.55) | CYP3A4TDP1ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115124570-B | Preparation method of C3 phosphine salt | 万华化学集团股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-104370793-B | Pyroles marine alkaloids Neolamellarin A analogs and its preparation method and application | 中国海洋大学 | 2017-10-17 | — | — | CN | disclosed |
| EP-2486070-B1 | INCREASE IN THE TOUGHNESS OF A MATERIAL ACHIEVED BY MEANS OF A CURABLE COMPOSITION INCLUDING AT LEAST ONE VINYL ESTER MONOMER | AIRBUS SAFRAN LAUNCHERS SAS (FR) | 2017-05-17 | — | — | EP | disclosed |
| US-8618186-B2 | Increase in the toughness of a material obtained from a curable composition comprising at least one vinyl ester monomer | ASTRIUM SAS (FR) | 2013-12-31 | — | — | US | disclosed |
| US-20120277383-A1 | INCREASE IN THE TOUGHNESS OF A MATERIAL OBTAINED FROM A CURABLE COMPOSITION COMPRISING AT LEAST ONE VINYL ESTER MONOMER | ASTRIUM SAS (FR) | 2012-11-01 | — | — | US | disclosed |
| EP-2486070-A1 | INCREASE IN THE TOUGHNESS OF A MATERIAL ACHIEVED BY MEANS OF A CURABLE COMPOSITION INCLUDING AT LEAST ONE VINYL ESTER MONOMER | Astrium SAS (FR) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011042554-A1 | INCREASE IN THE TOUGHNESS OF A MATERIAL ACHIEVED BY MEANS OF A CURABLE COMPOSITION INCLUDING AT LEAST ONE VINYL ESTER MONOMER | ASTRIUM SAS (FR) | 2011-04-14 | — | — | WO | disclosed |
| CN-101237892-A | Method for conjugating molecules containing an aminothiol to a carrier | AMGEN INC (US) | 2008-08-06 | — | — | CN | disclosed |
| EP-1848463-A2 | METHOD OF CONJUGATING AMINOTHIOL CONTAINING MOLECULES TO VEHICLES | Amgen Inc. (US) | 2007-10-31 | — | — | EP | disclosed |
| US-20060199812-A1 | Method of conjugating aminothiol containing molecules to vehicles | AMGEN INC. | 2006-09-07 | — | — | US | disclosed |
| WO-2006079099-A2 | METHOD OF CONJUGATING AMINOTHIOL CONTAINING MOLECULES TO A POLYMER | AMGEN INC. (US) | 2006-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199812-A1 | Method of conjugating aminothiol containing molecules to vehicles | SLC7A1, QPCT, SLC7A5 | CYP3A4 3682/4885TDP1 1848/4885ESR1 3904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.